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Jaw mobility changes in patients with upper aerodigestive tract cancer undergoing radiation therapy

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Jaw mobility changes in patients with upper aerodigestive tract cancer undergoing radiation therapy

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dc.contributor.author Bragante, Karoline es
dc.contributor.author Wienandts, Patrícia es
dc.contributor.author Mozzini, Carolina es
dc.contributor.author Pinto, Rosélie es
dc.contributor.author da Motta, Neiro es
dc.contributor.author Jotz, Geraldo es
dc.date.accessioned 2016-01-20T11:01:36Z
dc.date.available 2016-01-20T11:01:36Z
dc.date.issued 2015 es
dc.identifier.citation Bragante, Karoline ; Wienandts, Patrícia ; Mozzini, Carolina ; Pinto, Rosélie ; da Motta, Neiro ; Jotz, Geraldo. Jaw mobility changes in patients with upper aerodigestive tract cancer undergoing radiation therapy. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2015, Vol. 20, No. 6: 1- es
dc.identifier.uri http://hdl.handle.net/10550/50137
dc.description.abstract Background: Radiation therapy is a therapeutic modality widely used for treatment of upper aerodigestive tract (UADT) neoplasms. However, its action is not restricted to tumor cells, and it may cause a variety of adverse reactions, including reduced jaw mobility. Material and Methods: A prospective cohort study was conducted to assess changes in jaw mobility in patients with UADT cancer undergoing radiation therapy. Results: Fifty-six patients completed the study. The results showed a significant reduction in mouth opening ( p <0.001), right lateral excursion ( p =0.038) and left lateral excursion ( p =0.035) of the jaw, a significant increase in the presence ( p <0.001) and severity of oral mucositis ( p <0.001), and a significant decrease in performance status ( p <0.001) after radiation therapy. Thirty-six patients (64.3%) exhibited reduction in mouth opening after treatment. The variables significantly associated with mouth opening reduction on bivariate analysis were: modification of diet ( p =0.037), radiation field ( p =0.024), presence of mucositis ( p =0.003), and reduction in performance status ( p =0.007). After adjustment by the multivariate model, the only variables that remained significantly associated with reduction in mouth opening were presence of mucositis ( p =0.018) and reduction in performance status ( p =0.47). Conclusions: These findings indicate that patients with upper aerodigestive tract cancer experience reduced jaw mobility after radiation therapy, which is strongly correlated with mucositis and reduced functional ability. es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Jaw mobility changes in patients with upper aerodigestive tract cancer undergoing radiation therapy es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES
dc.identifier.url http://dialnet.unirioja.es/servlet/citart?info=link&codigo=5277072&orden=0 es

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