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Antimicrobial effects of Citrus sinensis peel extracts against dental caries bacteria: an in vitro study

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Antimicrobial effects of Citrus sinensis peel extracts against dental caries bacteria: an in vitro study

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dc.contributor.author Shetty, Sapna B. es
dc.contributor.author Mahin-Syed-Ismail, Prabu es
dc.contributor.author Varghese, Shaji es
dc.contributor.author Thomas-George, Bibin es
dc.contributor.author Kandathil- Thajuraj, Pathinettam es
dc.contributor.author Baby, Deepak es
dc.contributor.author Haleem, Shaista es
dc.contributor.author Sreedhar, Sreeja es
dc.contributor.author Devang-Divakar, Darshan es
dc.date.accessioned 2016-02-22T09:21:24Z
dc.date.available 2016-02-22T09:21:24Z
dc.date.issued 2016 es
dc.identifier.citation Shetty, Sapna B. ; Mahin-Syed-Ismail, Prabu ; Varghese, Shaji ; Thomas-George, Bibin ; Kandathil- Thajuraj, Pathinettam ; Baby, Deepak ; Haleem, Shaista ; Sreedhar, Sreeja ; Devang-Divakar, Darshan. Antimicrobial effects of Citrus sinensis peel extracts against dental caries bacteria: an in vitro study. En: Journal of Clinical and Experimental Dentistry, 2016, Vol. 8, No. 1: 71-77 es
dc.identifier.uri http://hdl.handle.net/10550/50987
dc.description.abstract Background: Ethnomedicine is gaining admiration since years but still there is abundant medicinal flora which is unrevealed through research. The study was conducted to assess the in vitro antimicrobial potential and also determine the minimum inhibitory concentration (MIC) of Citrus sinensis peel extracts with a view of searching a novel extract as a remedy for dental caries pathogens. Material and Methods: Aqueous and ethanol (cold and hot) extracts prepared from peel of Citrus sinensis were screened for in vitro antimicrobial activity against Streptococcus mutans and Lactobacillus acidophilus , using agar well diffusion method. The lowest concentration of every extract considered as the minimal inhibitory concentration (MIC) values were determined for both test organisms. One way ANOVA with Post Hoc Bonferroni test was applied for statistical analysis. Confidence level and level of significance were set at 95% and 5% respectively. Results: Dental caries pathogens were inhibited most by hot ethanolic extract of Citrus sinensis peel followed by cold ethanolic extract. Aqueous extracts were effective at very high concentrations. Minimum inhibitory concentration of hot and cold ethanolic extracts of Citrus sinensis peel ranged between 12-15 mg/ml against both the dental caries pathogens. Conclusions: Citrus sinensis peels extract was found to be effective against dental caries pathogens and contain compounds with therapeutic potential. Nevertheless, clinical trials on the effect of these plants are essential before advocating large-scale therapy en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Antimicrobial effects of Citrus sinensis peel extracts against dental caries bacteria: an in vitro study es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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