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Use of leukocyte and platelet-rich fibrin (L-PRF) in periodontally accelerated osteogenic orthodontics (PAOO): clinical effects on edema and pain

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Use of leukocyte and platelet-rich fibrin (L-PRF) in periodontally accelerated osteogenic orthodontics (PAOO): clinical effects on edema and pain

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dc.contributor.author Muñoz, Francisco es
dc.contributor.author Jiménez, Constanza es
dc.contributor.author Espinoza, Daniela es
dc.contributor.author Vervelle, Alain es
dc.contributor.author Beugnet, Jacques es
dc.contributor.author Haidar, Ziyad es
dc.date.accessioned 2016-05-26T09:33:01Z
dc.date.available 2016-05-26T09:33:01Z
dc.date.issued 2016 es
dc.identifier.citation Muñoz, Francisco ; Jiménez, Constanza ; Espinoza, Daniela ; Vervelle, Alain ; Beugnet, Jacques ; Haidar, Ziyad. Use of leukocyte and platelet-rich fibrin (L-PRF) in periodontally accelerated osteogenic orthodontics (PAOO): clinical effects on edema and pain. En: Journal of Clinical and Experimental Dentistry, 2016, Vol. 8, No. 2: 119-124 es
dc.identifier.uri http://hdl.handle.net/10550/53780
dc.description.abstract Background: Demand for shorter treatment time is common in orthodontic patients. Periodontally Accelerated Osteogenic Orthodontics (PAOO) is a somewhat new surgical procedure which allows faster tooth movement via combining orthodontic forces with corticotomy and grafting of alveolar bone plates. Leukocyte and Platelet-Rich Fibrin (L-PRF) possess hard- and soft-tissue healing properties. Further, evidence of pain-inhibitory and anti- inflammatory potential is growing. Therefore, this study explores the feasibility, intra- and post-operative effects of using L-PRF in PAOO in terms of post-operative pain, inflammation, infection and post-orthodontic stability. Material and Methods: A pilot prospective observational study involving a cohort of 11 patients was carried out. A Wilcko’s modified PAOO technique with L-PRF (incorporated into the graft and as covering membrane) was performed with informed consent. Post-surgical pain, inflammation and infection were recorded for 10 days post- operatively, while the overall orthodontic treatment and post-treatment stability were followed up to 2 years. Results: Accelerated wound healing with no signs of infection or adverse reactions was evident. Post-surgical pain was either “mild” (45.5%) or “moderate” (54.5%). Immediate post-surgical inflammation was either “mild” (89.9%) or “moderate” (9.1%). Resolution began on day 4 where most patients experienced either “mild” or no inflammation (72.7% and 9.1%, respectively). Complete resolution was achieved in all patients by day 8. The average orthodontic treatment time was 9.3 months. All cases were deemed stable for 2 years. Conclusions: L-PRF is simple and safe to use in PAOO. Combination with traditional bone grafts potentially accelerates wound healing and reduces post-surgical pain, inflammation, infection without interfering with tooth movement and/or post-orthodontic stability, over a 2 years period; thus alleviating the need for analgesics and anti-inflammatory medications. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Use of leukocyte and platelet-rich fibrin (L-PRF) in periodontally accelerated osteogenic orthodontics (PAOO): clinical effects on edema and pain es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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