Objectives. The purpose of this in vitro study were to determine variation in maxillary and mandibular vertical measurements and to assess vertical bone loss made from panoramic radiographs in edentulous measurements. Study Design. In this descriptive study, a total of 600 panoramic radiograph’s of edentulous patient were examined. The mean ages of edentulous patients were 31 and 87 years respectively. Measurements were made from reference lines drawn from anatomic landmarks on standardized panoramic rediographs. All radiographs were made using a standardized manner by the same technician. Twelve sites were measured on every panoramic radiograph whenever possible, five sites in the maxilla and seven sites in the mandible. Results. In the maxilla all vertical measurements distance were significantly greater in the edentulous men than in the edentulous women (p<0,05). In the mandible all vertical measurements distance were significantly greater in the edentulous men than in the edentulous women (p<0,05). Conclusion. The results of this study may guide clinicians to make primer decision of implant insertion area for implant supported prosthesis in edentulous patients