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Effect of different cryosurgical protocols using liquid nitrogen on bone tissue: a histomorphological analyze

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Effect of different cryosurgical protocols using liquid nitrogen on bone tissue: a histomorphological analyze

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dc.contributor.author Gurgel Costa, Fábio Wildson es
dc.contributor.author Brito, Gerly Anne de Castro es
dc.contributor.author Pessoa, Rosana Maria Andrade es
dc.contributor.author Studart Soares, Eduardo Costa es
dc.date.accessioned 2016-06-20T07:12:02Z
dc.date.available 2016-06-20T07:12:02Z
dc.date.issued 2011 es
dc.identifier.citation Gurgel Costa, Fábio Wildson ; Brito, Gerly Anne de Castro ; Pessoa, Rosana Maria Andrade ; Studart Soares, Eduardo Costa . Effect of different cryosurgical protocols using liquid nitrogen on bone tissue: a histomorphological analyze. En: Journal of Clinical and Experimental Dentistry, 2011, Vol. 3, No. 2: 91-96 es
dc.identifier.uri http://hdl.handle.net/10550/54112
dc.description.abstract The aim of the present experimental study was to evaluate the morphological effects of different liquid nitrogen cryosurgery protocols on bone tissue. The femoral diaphyses of 42 Wistar rats were exposed to three local and sequential applications of liquid nitrogen for 1 or 2 min, intercalated with periods of 5 min of passive thawing. The animals were sacrificed after 1, 2, 4 and 12 weeks and the specimens obtained were processed and analyzed histomorphologically. Histologically, an increase in bone necrosis was observed for the two protocols in the second week after cryotherapy. A significant osteogenic phase was observed after 4 weeks. Moreover, complete remodeling process was encountered at the end of the morphological observation period (12 weeks), especially on oneminute protocol. Thus, this study indicated that the 2-min protocol produced more marked bone necrosis than the 1-min protocol. In addition, the second experimental week was critical for bone necrosis with either cryotherapy protocol. Further studies are important for the understanding of the long-term behavior of bone tissue after cryoapplication of liquid nitrogen en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Effect of different cryosurgical protocols using liquid nitrogen on bone tissue: a histomorphological analyze es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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