NAGIOS: RODERIC FUNCIONANDO

Highly enantioselective copper(I)-catalyzed conjugate addition of 1,3-diynes to α,β-unsaturated trifluoromethyl ketones

Repositori DSpace/Manakin

dc.contributor.author	Sanz Marco, Amparo
dc.contributor.author	Blay Llinares, Gonzalo
dc.contributor.author	Muñoz, M. Carmen
dc.contributor.author	Pedro, José Ramón
dc.date.accessioned	2016-06-20T14:27:32Z
dc.date.available	2016-06-20T14:27:32Z
dc.date.issued	2015
dc.identifier.citation	Sanz Marco, Amparo Blay Llinares, Gonzalo Muñoz, M. Carmen Pedro, José Ramón 2015 Highly enantioselective copper(I)-catalyzed conjugate addition of 1,3-diynes to α,β-unsaturated trifluoromethyl ketones Chemical Communications 51 8958 8961
dc.identifier.uri	http://hdl.handle.net/10550/54140
dc.description.abstract	The conjugate diynylation of a,b-unsaturated trifluoromethyl ketones is carried out in the presence of a low catalytic load (2.5 mol%) of a copper(I)-MeOBIPHEP complex, triethylamine and a terminal 1,3-diyne. Pre-metalation of the terminal 1,3-diyne with stoichiometric or higher amounts of dialkylzinc reagent is not required. The corresponding internal diynes bearing a propargylic stereogenic center are obtained with good yields and excellent enantioselectivities.
dc.language.iso	eng
dc.relation.ispartof	Chemical Communications, 2015, vol. 51, p. 8958-8961
dc.subject	Catàlisi
dc.subject	Química orgànica
dc.title	Highly enantioselective copper(I)-catalyzed conjugate addition of 1,3-diynes to α,β-unsaturated trifluoromethyl ketones
dc.type	journal article	es_ES
dc.date.updated	2016-06-20T14:27:33Z
dc.identifier.doi	10.1039/c5cc01676b
dc.identifier.idgrec	102840
dc.rights.accessRights	open access	es_ES