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Central Odontogenic Fibroma combined with Central Giant Cell lesion of the mandible. Immunohistochemical profile.

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Central Odontogenic Fibroma combined with Central Giant Cell lesion of the mandible. Immunohistochemical profile.

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dc.contributor.author Bologna-Molina, Ronell es
dc.contributor.author Pacheco Ruiz, Laura es
dc.contributor.author Mosqueda Taylor, Adalberto es
dc.contributor.author Huesca Ramirez, Héctor Gustavo es
dc.contributor.author Ponce Lonato, José Angel es
dc.contributor.author González González, Rogelio es
dc.date.accessioned 2016-06-24T12:18:11Z
dc.date.available 2016-06-24T12:18:11Z
dc.date.issued 2011 es
dc.identifier.citation Bologna-Molina, Ronell ; Pacheco Ruiz, Laura ; Mosqueda Taylor, Adalberto ; Huesca Ramirez, Héctor Gustavo ; Ponce Lonato, José Angel ; González González, Rogelio. Central Odontogenic Fibroma combined with Central Giant Cell lesion of the mandible. Immunohistochemical profile.. En: Journal of Clinical and Experimental Dentistry, 2011, Vol. 3, No. 4: 348-351 es
dc.identifier.uri http://hdl.handle.net/10550/54211
dc.description.abstract Central Odontogenic Fibroma is a benign neoplasm of mesenchymal origin that makes up less than 5% of odontogenic tumors. There is a variation of this lesion that includes a zone of giant cells. This neoplasm is characterized by fibroblast proliferation, a component of apparently inactive odontogenic epithelium within a mature connective tissue stroma and multinucleated osteoclast-like giant cells. Clinically, it manifests as a slow-growing central lesion, which causes painless cortical expansion and may occasionally cause the displacement of adjacent dental organs or resorption. We present a new case of this combined lesion that was revealed radiographically as a well-defined radiolucent area in the left mandibular body. Histologically, we identified a mesenchymal lesion composed of mature fibrocellular tissue, where islands and cords of odontogenic epithelium and fibrocellular areas with numerous giant cells can be distinguished. The immunohistochemical examination was positive for giant cells with the marker CD68 and positive for epithelium cords with the marker CK19, which indicates that this an odontogenic lesion. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Central Odontogenic Fibroma combined with Central Giant Cell lesion of the mandible. Immunohistochemical profile. es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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