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Clinical findings and risk factors to oral squamous cell carcinoma in young patients: a 12-year retrospective analysis

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Clinical findings and risk factors to oral squamous cell carcinoma in young patients: a 12-year retrospective analysis

dc.contributor.author	Santos, Hellen-Bandeira-de-Pontes	es
dc.contributor.author	dos Santos, Thayana-Karla-Guerra	es
dc.contributor.author	Paz, Alexandre-Rolim	es
dc.contributor.author	Cavalcanti, Yuri-Wanderley	es
dc.contributor.author	Nonaka, Cassiano-Francisco-Weege	es
dc.contributor.author	Godoy, Gustavo-Pina	es
dc.contributor.author	Alves, Pollianna-Muniz	es
dc.date.accessioned	2016-07-26T11:49:34Z
dc.date.available	2016-07-26T11:49:34Z
dc.date.issued	2016	es
dc.identifier.citation	Santos, Hellen-Bandeira-de-Pontes ; dos Santos, Thayana-Karla-Guerra ; Paz, Alexandre-Rolim ; Cavalcanti, Yuri-Wanderley ; Nonaka, Cassiano-Francisco-Weege ; Godoy, Gustavo-Pina ; Alves, Pollianna-Muniz. Clinical findings and risk factors to oral squamous cell carcinoma in young patients: a 12-year retrospective analysis. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2016, : 151-	es
dc.identifier.uri	http://hdl.handle.net/10550/54735
dc.description.abstract	Background: In recent years have been observed an increased incidence of OSCC in young individuals. Based on this, the aim this study was to describe the clinical characteristics of all cases of OSCC in younger patients, diagnosed in two oncology referral hospitals, at the northeast region of Brazil within a 12-year period. Material and Methods: Data regarding general characteristics of patients (age, gender and tobacco and/or alcohol habits) and information about the lesions (tumor location, size, regional lymph node metastasis, distant metastasis and clinical stage) were submitted to descriptive and inferential analysis. Statistical analysis included Chi-square and Fisher’s exact tests (P<0.05). Results: Out of 2311 registered cases of OSCC, 76 (3.3%) corresponded to OSCC in patients under 45 years old. Most of them were male (n=62, 81.6%) and tobacco and/or alcohol users (n=40, 52.8%). The most frequent site was the tongue (n=31, 40.8%), with predominance of cases classified at advanced clinical stage (III and IV, n = 46, 60.5%). The advanced stage of OSCC (III and IV) was statistically associated with male gender (P=0.035), lower education level (P=0.007), intraoral sites (P<0.001), presence of pain symptomatology (P=0.006), and consumption of tobacco and/or alcohol (P=0.001). Conclusions: The profile of OSCC in young patients resembles to the commonly characteristics reported for overall population. The late diagnosis in young patients usually results in poor prognosis, associated with gender, harmful habits and tumor location. Although prevalence is low, stimulus to prevention and to early diagnosis should be addressed to young individuals exposed to risk factors	en_US
dc.relation		es
dc.subject	Odontología	es
dc.subject	Ciencias de la salud	es
dc.title	Clinical findings and risk factors to oral squamous cell carcinoma in young patients: a 12-year retrospective analysis	es
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS	es
dc.type.hasVersion	VoR	es_ES