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Efficacy of light based detection systems for early detection of oral cancer and oral potentially malignant disorders: systematic review

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Efficacy of light based detection systems for early detection of oral cancer and oral potentially malignant disorders: systematic review

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dc.contributor.author Nagi, Ravleen es
dc.contributor.author Reddy-Kantharaj, Yashoda-Bhoomi es
dc.contributor.author Rakesh, Nagaraju es
dc.contributor.author Janardhan-Reddy, Sujatha es
dc.contributor.author Sahu, Shashikant es
dc.date.accessioned 2016-07-26T12:01:04Z
dc.date.available 2016-07-26T12:01:04Z
dc.date.issued 2016 es
dc.identifier.citation Nagi, Ravleen ; Reddy-Kantharaj, Yashoda-Bhoomi ; Rakesh, Nagaraju ; Janardhan-Reddy, Sujatha ; Sahu, Shashikant. Efficacy of light based detection systems for early detection of oral cancer and oral potentially malignant disorders: systematic review. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2016, Vol. 21, No. 4: 447- es
dc.identifier.uri http://hdl.handle.net/10550/54793
dc.description.abstract Background: Earlier detection of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) is essential for dental professionals to improve patient survival rates. The aim of this systematic review is to to evaluate the effectiveness of devices that utilise the principles of chemiluminescence and tissue autofluorescence as adjuncts in the detection of OSCC and OPMD. Material and Methods: The electronic retrieval systems and databases searched for relevant articles were PubMed [MEDLINE] and Science direct. The search was for limited articles published in English or with an English abstract and articles published during the period from January 2005 to April 2014. Clinical trials utilized ViziLite, Microlux TM/DL and Visual Enhanced Light scope (VELscope) for early detection of OPMD and OSCC. Results: Twenty primary studies published satisfied our criteria for selection - 10 utilised chemiluminescence and 10 tissue autofluorescence. Senstivity of Vizilite for detecting OSCC nad OPMD ranged from 77.1 % to 100% and specificity was low that ranged from 0% to 27.8%.Most have shown that chemiluminescence increases the brightness and margins of oral mucosal white lesions and thus assist in identification of mucosal lesions not considered under Conventional visual examination. However, it preferentially detects leukoplakia and may fail to spot red patches. Clinical trials demonstrated that sensitivity of VELscope in detecting malignancy and OPMD ranged from 22 % to 100 % and specificity ranged from 16 % to 100%. Most studies concluded that VELscope can help the experienced clinician to find oral precursor malignant lesions. But it couldnot differentiate between dysplasia and benign inflammatory conditions. Conclusions: Both devices are simple, non-invasive test of the oral mucosa but are suited for clinicians with sufficient experience and training. More clinical trials in future should be conducted to establish optical imaging as an efficacious adjunct tool in early diagnosis of OSCC and OPMD. en_US
dc.relation es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Efficacy of light based detection systems for early detection of oral cancer and oral potentially malignant disorders: systematic review es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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