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Effectiveness of amlexanox and adcortyl for the treatment of recurrent aphthous ulcers

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Effectiveness of amlexanox and adcortyl for the treatment of recurrent aphthous ulcers

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dc.contributor.author Abbasi, Farid es
dc.contributor.author Raoof, Maryam es
dc.contributor.author Khatami, Roya es
dc.contributor.author Shadman, Niloofar es
dc.contributor.author Borjian Boroojeni, Farnaz es
dc.contributor.author Nazari, Farahnaz es
dc.date.accessioned 2017-03-06T08:29:49Z
dc.date.available 2017-03-06T08:29:49Z
dc.date.issued 2016 es
dc.identifier.citation Abbasi, Farid ; Raoof, Maryam ; Khatami, Roya ; Shadman, Niloofar ; Borjian Boroojeni, Farnaz ; Nazari, Farahnaz. Effectiveness of amlexanox and adcortyl for the treatment of recurrent aphthous ulcers. En: Journal of Clinical and Experimental Dentistry. 2016. Vol. 8, no. 4: 368 es
dc.identifier.uri http://hdl.handle.net/10550/57526
dc.description.abstract Background: Recurrent aphthous stomatitis (RAS) is a common condition that affects approximately 20% of the general population. The ulcers can interfere with speech and eating and cause significant pain and discomfort. This study aimed to evaluate the efficacy of Amlexanox and Adcortyl in the treatment of aphthous ulcers. Material and Methods: In this randomized double blind clinical trial with sequential patient entry, a total of 40 patients who presented with aphthous ulcers were included. Patients were received Amlexanox or Adcortyl four times daily for 7 days. Patients were evaluated for pain, lesion size, and tingling at one day, three days, five days and seven days follow-ups. The treatment effects were then evaluated using the Wilcoxonâ Mannâ Whitney (WMW) test. Values of p<0.05 were considered significant. Results: No significant differences in pain score, tingling and lesion size were observed on similar days between Amlexanox and Adcortyl groups. In both groups, reduction in the assessed variables was significant between days 1-3, 3-5, and 5-7 (p < 0.001). Conclusions: This study indicated that Amlexanox as well as Adcortyl was effective in relieving pain and reducing the lesion size during the treatment of aphthous ulcers. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Effectiveness of amlexanox and adcortyl for the treatment of recurrent aphthous ulcers es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÃ DICAS es
dc.type.hasVersion VoR es_ES

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