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Mandibular destructive radiolucent lesion: the first sign of multiple myeloma

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Mandibular destructive radiolucent lesion: the first sign of multiple myeloma

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dc.contributor.author Fregnani, Eduardo Rodrigues es
dc.contributor.author Leite, Amanda Almeida es
dc.contributor.author Parahyba, Claudia Joffily es
dc.contributor.author Nesrallah, Ana Cristina Alo es
dc.contributor.author Ramos Perez, Flávia Maria de Moraes es
dc.contributor.author Perez, Danyel Elias da Cruz es
dc.date.accessioned 2017-03-06T08:32:16Z
dc.date.available 2017-03-06T08:32:16Z
dc.date.issued 2016 es
dc.identifier.citation Fregnani, Eduardo Rodrigues ; Leite, Amanda Almeida ; Parahyba, Claudia Joffily ; Nesrallah, Ana Cristina Alo ; Ramos Perez, Flávia Maria de Moraes ; Perez, Danyel Elias da Cruz. Mandibular destructive radiolucent lesion: the first sign of multiple myeloma. En: Journal of Clinical and Experimental Dentistry. 2016. Vol. 8, no. 4: 465 es
dc.identifier.uri http://hdl.handle.net/10550/57541
dc.description.abstract The occurrence of a mandibular lesion as the first sign of multiple myeloma (MM) is uncommon. This report describes a case of MM diagnosed because of a mandibular lesion. A 62-year-old woman presented a destructive radiolucent lesion in the right mandibular ramus. The lesion caused rupture of the anterior cortical bone and extended from the retromolar area to the coronoid process. An incisional biopsy was performed. Histopathological examination revealed numerous pleomorphic plasma cells, some with binucleated nuclei. The tumor cells showed kappa lightchain restriction. Bone marrow biopsy showed findings of massive infiltration of neoplastic plasma cells, besides lesions in the vertebrae. The diagnosis of MM was established. The patient underwent autologous hematopoietic stem-cell transplantation. Currently, the patient is under regular follow up after 40 months of initial treatment. In conclusion, MM should be considered in the differential diagnosis of destructive mandibular lesions. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Mandibular destructive radiolucent lesion: the first sign of multiple myeloma es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÃ DICAS es
dc.type.hasVersion VoR es_ES

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