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Adverse systemic reaction to benznidazole.

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Adverse systemic reaction to benznidazole.

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dc.contributor.author Pacheco Coronel, Maria Verónica
dc.contributor.author Oriente Frutos, Laura
dc.contributor.author Calabuig Muñoz, Eva
dc.contributor.author Kury Valle, Diana
dc.contributor.author Hernández Fernández de Rojas, Dolores
dc.date.accessioned 2017-05-08T08:10:44Z
dc.date.available 2017-05-08T08:10:44Z
dc.date.issued 2017
dc.identifier.citation Pacheco Coronel, Maria Verónica Oriente Frutos, Laura Calabuig Muñoz, Eva Kury Valle, Diana Hernández Fernández de Rojas, Dolores 2017 Adverse systemic reaction to benznidazole. Revista Da Sociedade Brasileira de Medicina Tropical 50 1 145 147
dc.identifier.uri http://hdl.handle.net/10550/58383
dc.description.abstract Benznidazole, drug of choice for Chagas disease (CD), has been associated with a high incidence of adverse reactions that can become serious, necessitating discontinuation of the drug. We describe the case of a Bolivian patient living in Spain for 9 years, who, following treatment with benznidazole for CD in indeterminate chronic phase, presented with fever, skin lesions, digestive symptoms, general malaise, and laboratory abnormalities. After the discontinuation of benznidazole and, the intake of antihistamines and systemic corticosteroids, the patient presented a complete resolution of the symptoms. Optimization of dose strategies and development of more effective, and better-tolerated drugs is advisable.
dc.language.iso eng
dc.relation.ispartof Revista Da Sociedade Brasileira de Medicina Tropical, 2017, vol. 50, num. 1, p. 145-147
dc.subject Farmacologia
dc.subject Chagas, Malaltia de
dc.title Adverse systemic reaction to benznidazole.
dc.type journal article es_ES
dc.date.updated 2017-05-08T08:10:44Z
dc.identifier.idgrec 117280
dc.rights.accessRights open access es_ES

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