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Towards clinical application of RayStretch for heterogeneity corrections in LDR permanent 125-I prostate brachytherapy

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Towards clinical application of RayStretch for heterogeneity corrections in LDR permanent 125-I prostate brachytherapy

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dc.contributor.author	Hueso González, Fernando
dc.contributor.author	Ballester Pallarés, Facundo
dc.contributor.author	Pérez Calatayud, José
dc.contributor.author	Siebert, Frank-André
dc.contributor.author	Vijande Asenjo, Javier
dc.date.accessioned	2017-05-08T14:43:49Z
dc.date.available	2018-04-05T04:45:05Z
dc.date.issued	2017
dc.identifier.citation	Hueso González, Fernando Ballester Pallarés, Facundo Pérez Calatayud, José Siebert, Frank-André Vijande Asenjo, Javier 2017 Towards clinical application of RayStretch for heterogeneity corrections in LDR permanent 125-I prostate brachytherapy Brachytherapy 16 3 616 623
dc.identifier.uri	http://hdl.handle.net/10550/58398
dc.description.abstract	Purpose: RayStretch is a simple algorithm proposed for heterogeneity corrections in low-dose-rate brachytherapy. It is built on top of TG-43 consensus data, and it has been validated with Monte Carlo (MC) simulations. In this study, we take a real clinical prostate implant with 71 125I seeds as reference and we apply RayStretch to analyze its performance in worst-case scenarios. Methods and Materials: To do so, we design two cases where large calcifications are located in the prostate lobules. RayStretch resilience under various calcification density values is also explored. Comparisons against MC calculations are performed. Results: Dose-volume histogram-related parameters like prostate D90, rectum D2cc, or urethra D10 obtained with RayStretch agree within a few percent with the detailed MC results for all cases considered. Conclusions: The robustness and compatibility of RayStretch with commercial treatment planning systems indicate its applicability in clinical practice for dosimetric corrections in prostate calcifications. Its use during intraoperative ultrasound planning is foreseen.
dc.language.iso	eng
dc.relation.ispartof	Brachytherapy, 2017, vol. 16, num. 3, p. 616-623
dc.subject	Braquiteràpia
dc.subject	Pròstata
dc.title	Towards clinical application of RayStretch for heterogeneity corrections in LDR permanent 125-I prostate brachytherapy
dc.type	journal article	es_ES
dc.date.updated	2017-05-08T14:43:49Z
dc.identifier.doi	10.1016/j.brachy.2017.02.005
dc.identifier.idgrec	117221
dc.embargo.terms	1 year
dc.rights.accessRights	open access	es_ES