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Keratocystic odontogenic tumor : a biopsy service?s experience with 104 solitary, multiple and recurrent lesions

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Keratocystic odontogenic tumor : a biopsy service?s experience with 104 solitary, multiple and recurrent lesions

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dc.contributor.author Bello, Ibrahim-Olajide es
dc.date.accessioned 2017-07-21T07:51:25Z
dc.date.available 2017-07-21T07:51:25Z
dc.date.issued 2016 es
dc.identifier.citation Bello, Ibrahim-Olajide. Keratocystic odontogenic tumor : a biopsy service?s experience with 104 solitary, multiple and recurrent lesions. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 21 5 2016: 2- es
dc.identifier.uri http://hdl.handle.net/10550/59753
dc.description.abstract Keratocystic odontogenic tumor (KCOT) is a clinically significant cystic lesion of odontogenic origin. This study aimed to retrospectively review and describe the clinicopathologic features of KCOT and to objectively compare the clinical and histological features of solitary, multiple and recurrent KCOT in a Saudi Arabian population. Biopsy request forms, pathology records and archival materials (all histological slides) of 104 cases of KCOT from 75 patients were retrieved. Demographic and clinical details as well as histological evaluation were analyzed and compared between the 3 groups using chi-squared or Mann-Whitney tests of association as appropriate. Significant differences were noted in the age of presentation, location and association with impaction between multiple and solitary cases. Histologically, there was a difference in the mitotic count, presence of satellite cysts and proliferating odontogenic epithelium between solitary and multiple lesions. There was no difference between the KCOT that later recurred and solitary lesion which did not recur even when matched clinically for age, sex and location. There were differences when solitary KCOT that later recurred or recurrent KCOT were compared with multiple lesions. Multiple lesions still had more significant proliferative activity parameters than solitary recurrence-related KCOT. KCOTs in Saudi Arabians are not different from those reported from other parts of the world. Clinical and histological analyses showed multiple KCOT is different from its solitary recurrent or non-recurrent counterparts and has a higher proliferative activity than both. Clinicohistologic features alone cannot wholly explain the behavior of KCOT. es
dc.title Keratocystic odontogenic tumor : a biopsy service?s experience with 104 solitary, multiple and recurrent lesions es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.21181 es
dc.type.hasVersion VoR es_ES

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