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Dabigatran : a new oral anticoagulant. Guidelines to follow in oral surgery procedures. A systematic review of the literature

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Dabigatran : a new oral anticoagulant. Guidelines to follow in oral surgery procedures. A systematic review of the literature

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dc.contributor.author Muñoz Corcuera, Marta es
dc.contributor.author Ramírez Martínez Acitores, Lucía es
dc.contributor.author López-Pintor Muñoz, Rosa Mª es
dc.contributor.author Casañas Gil, Elisabeth es
dc.contributor.author Hernández Vallejo, Gonzalo es
dc.date.accessioned 2017-07-21T10:17:17Z
dc.date.available 2017-07-21T10:17:17Z
dc.date.issued 2016 es
dc.identifier.citation Muñoz Corcuera, Marta ; Ramírez Martínez Acitores, Lucía ; López-Pintor Muñoz, Rosa Mª ; Casañas Gil, Elisabeth ; Hernández Vallejo, Gonzalo. Dabigatran : a new oral anticoagulant. Guidelines to follow in oral surgery procedures. A systematic review of the literature. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 21 6 2016: 13- es
dc.identifier.uri http://hdl.handle.net/10550/59776
dc.description.abstract Dabigatran is a newly commercialized drug that is replacing other anticoagulants in the prevention of venous thromboembolism, stroke and systemic arterial valve embolism. It acts directly on thrombin presenting in a dynamic and predictable way, which does not require monitoring these patients. Therefore, we consider the need to assess whether their use increases the risk of bleeding involved before any dental treatment. We performed a systematic review with a bibliographic search in PubMed/Medline along with the Cochrane Library. We excluded articles dealing with all anticoagulants other than dabigatran, and works about surgical treatments in anatomical locations other than the oral cavity. We included a total of 13 papers of which 1 was a randomized clinical trial, 9 narrative literature reviews, 1 case series, 2 clinical cases and 1 expert opinion. Because we did not obtain any properly designed clinical trials, we were unable to conduct a meta-analysis. Currently, there is no consensus on the procedure to be followed in patients taking dabigatran. However, all authors agree to treat each case individually in accordance to the risk of embolism, postoperative bleeding and renal function. Also, it is necessary to perform minimally invasive interventions, and take the appropriate local anti-hemolytic measures. es
dc.title Dabigatran : a new oral anticoagulant. Guidelines to follow in oral surgery procedures. A systematic review of the literature es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.21202 es
dc.type.hasVersion VoR es_ES

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