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The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction

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The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction

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dc.contributor.author Madrazo Jiménez, Marta es
dc.contributor.author Rodríguez Caballero, Ángela es
dc.contributor.author Serrera Figallo, María Angeles es
dc.contributor.author Garrido Serrano, Roberto es
dc.contributor.author Gutiérrez Corrales, Aida es
dc.contributor.author Gutiérrez Pérez, José Luis es
dc.contributor.author Torres-Lagares, Daniel es
dc.date.accessioned 2017-07-21T10:17:18Z
dc.date.available 2017-07-21T10:17:18Z
dc.date.issued 2016 es
dc.identifier.citation Madrazo Jiménez, Marta ; Rodríguez Caballero, Ángela ; Serrera Figallo, María Angeles ; Garrido Serrano, Roberto ; Gutiérrez Corrales, Aida ; Gutiérrez Pérez, José Luis ; Torres-Lagares, Daniel. The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 21 6 2016: 3- es
dc.identifier.uri http://hdl.handle.net/10550/59778
dc.description.abstract Despite efforts to prevent postoperative discomfort, there are still many immediate side effects associated with the surgical extraction of impacted lower third molars. Cicatrization is a physiological process through which the loss of integrity of oral mucosa is recovered and damaged tissues are repaired. Bexident Post (ISDIN, Spain) is a topical gel that contains chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol. While this gel has many clinical indications, there are no published clinical trials evaluating its use in impacted mandibular third molar surgery. This study aims to clinically evaluate the efficacy of a gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol on wound healing and reduction of postoperative side effects and complications after extraction of an impacted mandibular third molar. A split-mouth design study was carried out on a total of 50 bilaterally and symmetrically impacted third molar extractions, which were randomly placed into either a control group (CG=25) or an experimental group (EG=25). Patients were all informed of the purpose of the study and provided written consent. All procedures were carried out by the same dental practitioner, in accordance with standard surgical protocol. A different dental practitioner, unaware of which treatment had been applied, provided follow-up care. The EG applied 10 ml of topical gel composed of chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol to the surgical wound three times a day for 10 days, patients in the CG did not apply any gel. The groups were homogeneous insofar as potentially confounding variables. No significant findings were found regarding postoperative swelling and pain. Neither of the groups displayed poor healing or infectious complications of the wound during the postoperative period. In all the recorded follow-ups (Day 7 p=0.001, and Day 14 p=0.01), the wound?s aesthetic appearance was better in the EG. Overall treatment tolerance was satisfactory and similar in both groups. The gel composed of chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not aid in patients? postoperative comfort; however, improved wound healing was observed. es
dc.title The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.21281 es
dc.type.hasVersion VoR es_ES

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