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Eradication of enterococci biofilms by lactic acid alone and combined with chlorhexidine and cetrimide

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Eradication of enterococci biofilms by lactic acid alone and combined with chlorhexidine and cetrimide

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dc.contributor.author Arias Moliz, María Teresa es
dc.contributor.author Baca García, Pilar es
dc.contributor.author Ordóñez Becerra, Santiago es
dc.contributor.author González Rodríguez, Mª Paloma es
dc.contributor.author Ferrer Luque, Carmen María es
dc.date.accessioned 2017-07-24T11:03:27Z
dc.date.available 2017-07-24T11:03:27Z
dc.date.issued 2012 es
dc.identifier.citation Arias Moliz, María Teresa ; Baca García, Pilar ; Ordóñez Becerra, Santiago ; González Rodríguez, Mª Paloma ; Ferrer Luque, Carmen María. Eradication of enterococci biofilms by lactic acid alone and combined with chlorhexidine and cetrimide. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 17 5 2012: 12- es
dc.identifier.uri http://hdl.handle.net/10550/59875
dc.description.abstract Objective: The antimicrobial activity of lactic acid (LA) alone or in combination with chlorhexidine (CHX) and cetrimide (CTR) against three Enterococcus faecalis strains, E. faecalis ATCC 29212, E. faecalis EF- D1 and E. faecalis U-1765, one Enterococcus durans strain and one dual- species biofilm was investigated. Study Design: The irrigating solutions tested were 20%, 15%, 10%, 5% and 2.5% LA, alone and in combination with 2% CHX and with 0.2% CTR. The biofilms were grown in the MBEC TM high-throughput device for 24 hours and exposed to the solutions for 30 seconds and 1 minute. ?Eradication? was defined as 100% bacterial kill. Results: Twenty percent LA eradicated all enterococci biofilms after 30 seconds contact time. The association of LA + 0.2% CTR achieved better results than LA alone, in contrast with the results obtained using LA + 2% CHX. E. durans was eradicated by all the tested solutions at 1 minute. The dual- species biofilm, E. faecalis ATCC 29212 + E. durans, gave intermediate values of the pure cultures. Conclusions: LA is capable of eradicating enterococci biofilm at a concentration of 20%. The combination of lower concentrations with 0.2% CTR achieved eradication after 1 minute. es
dc.title Eradication of enterococci biofilms by lactic acid alone and combined with chlorhexidine and cetrimide es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.18133 es
dc.type.hasVersion VoR es_ES

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