NAGIOS: RODERIC FUNCIONANDO

The role of mast cells on angiogenesis in oral squamous cell carcinoma

Repositori DSpace/Manakin

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

The role of mast cells on angiogenesis in oral squamous cell carcinoma

Mostra el registre parcial de l'element

dc.contributor.author Kalra, Manpreet es
dc.contributor.author Rao, Nirmala es
dc.contributor.author Nanda, Kanwardeep es
dc.contributor.author Rehman, Farzan es
dc.contributor.author Girish, KL es
dc.contributor.author Tippu, Shoaib es
dc.contributor.author Arora, Asit es
dc.date.accessioned 2017-07-25T12:11:22Z
dc.date.available 2017-07-25T12:11:22Z
dc.date.issued 2012 es
dc.identifier.citation Kalra, Manpreet ; Rao, Nirmala ; Nanda, Kanwardeep ; Rehman, Farzan ; Girish, KL ; Tippu, Shoaib ; Arora, Asit. The role of mast cells on angiogenesis in oral squamous cell carcinoma. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 17 2 2012: 13- es
dc.identifier.uri http://hdl.handle.net/10550/59992
dc.description.abstract Objective: Angiogenesis or neovascularization has long been known to aid in progression and metastasis of malignant tumors. Tumor angiogenesis is a complex event mediated by angiogenic factors released from cancer cells and or by host immune cells. Mast cells may induce tumor progression and potentiate metastasis by stimulating angiogenesis. The purpose of the present study was to validate topographic distribution of micro vessel density (MVD) and mast cell density (MCD) and help to elucidate the possible role of mast cells in tumor angiogenesis and correlating this with advanced disease parameters. Study Design: MVD and MCD were investigated in tumor specimens from 30 patients diagnosed with different histologic grades of oral squamous cell carcinoma (OSCC). Intratumor vessels were stained with collagen Type IV antibody and mast cells with Toluidine blue before being measured by light microscopy. Results: There was a significant correlation between MVD and disease progression and number of blood vessels increased from well to poorly differentiated OSCC where as MCD decreased. Conclusions: These findings suggest that angiogenesis indeed occur in OSCC and might be used as an index to inflect the aggression of the disease however mast cells make up only a part of complex process of angiogenesis along with other factors secreted by tumor. © Medicina Oral S. L. es
dc.title The role of mast cells on angiogenesis in oral squamous cell carcinoma es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.17395 es
dc.type.hasVersion VoR es_ES

Visualització       (2.440Mb)

Aquest element apareix en la col·lecció o col·leccions següent(s)

Mostra el registre parcial de l'element

Cerca a RODERIC

Cerca avançada

Visualitza

Estadístiques