NAGIOS: RODERIC FUNCIONANDO

Applications of OralCDx ® methodology in the diagnosis of oral leukoplakia

Repositori DSpace/Manakin

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

Applications of OralCDx ® methodology in the diagnosis of oral leukoplakia

Mostra el registre parcial de l'element

dc.contributor.author Seijas Naya, Flavio es
dc.contributor.author García Carnicero, Tamara es
dc.contributor.author Gándara Vila, Pilar es
dc.contributor.author Couso Folgueiras, Elena es
dc.contributor.author Pérez-Sayáns, Mario es
dc.contributor.author Gándara Vila, Rafael es
dc.contributor.author García García, Abel es
dc.contributor.author Gándara Rey, José Manuel es
dc.date.accessioned 2017-07-26T06:41:16Z
dc.date.available 2017-07-26T06:41:16Z
dc.date.issued 2012 es
dc.identifier.citation Seijas Naya, Flavio ; García Carnicero, Tamara ; Gándara Vila, Pilar ; Couso Folgueiras, Elena ; Pérez-Sayáns, Mario ; Gándara Vila, Rafael ; García García, Abel ; Gándara Rey, José Manuel. Applications of OralCDx ® methodology in the diagnosis of oral leukoplakia. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 17 1 2012: 10- es
dc.identifier.uri http://hdl.handle.net/10550/60028
dc.description.abstract Objective: We aim to evaluate the effectiveness of the brush biopsy technique using OralCDx ® (OralScan Laboratories Inc., Suffern, NY) as a new method for early diagnosis and control of a 'potentially malignant disorder' such as oral leukoplakia. Design of the study: We performed a study in which samples were taken using OralCDx ® on 24 patients who visited the Master of Oral Medicine, Oral Surgery and Implantology of the University of Santiago de Compostela between February 2009 and May 2010. These patients presented clinical and histological lesions that were consistent with oral leukoplakia. We evaluated the relationship between the keratinization degree of the lesions and cell representation; the diagnosis obtained through OralCDx ® and biopsies; and sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV). Results: 50% of patients were men and 50% women with an average age of 62.38 years. The Kappa coefficient relating keratinization of lesions and cell representation was 0.33, the OralCDx ® - biopsy diagnostic rate reached a Kappa value of 0.66, recording 72.7%, sensitivity and 92.3% specificity, PPV was 88.8%, while NPV reached 80%. Conclusions: cytology sampling with OralCDx ® showed high sensitivity and specificity values, which make it a good tool for monitoring oral leukoplakia, but nowadays the most reliable method that allows us to confirm the exact diagnosis of the lesions and their anatomical and pathological characteristics still is conventional biopsy using a surgical scalpel. © Medicina Oral S. L. es
dc.title Applications of OralCDx ® methodology in the diagnosis of oral leukoplakia es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.17275 es
dc.type.hasVersion VoR es_ES

Visualització       (341.5Kb)

Aquest element apareix en la col·lecció o col·leccions següent(s)

Mostra el registre parcial de l'element

Cerca a RODERIC

Cerca avançada

Visualitza

Estadístiques