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Clinico-therapeutic management of osteoradionecrosis : a literature review and update

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Clinico-therapeutic management of osteoradionecrosis : a literature review and update

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dc.contributor.author Silvestre Rangil, Javier es
dc.contributor.author Silvestre Donat, Francisco Javier es
dc.date.accessioned 2017-07-26T08:27:09Z
dc.date.available 2017-07-26T08:27:09Z
dc.date.issued 2011 es
dc.identifier.citation Silvestre Rangil, Javier ; Silvestre Donat, Francisco Javier. Clinico-therapeutic management of osteoradionecrosis : a literature review and update. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 16 7 2011: 8- es
dc.identifier.uri http://hdl.handle.net/10550/60049
dc.description.abstract In the management of head and neck cancer, radiotherapy is usually a coadjuvant to surgery, or is applied on a palliative basis. The most important complication of such radiotherapy is osteoradionecrosis, which manifests as an area of exposed necrotic bone in the maxillae or mandible that fails to heal during at least three months. In most cases osteoradionecrosis gradually progresses, becoming more extensive and painful, and its late manifestations comprise infection and pathological fracture. The present study provides a literature review and update on the risk factors underlying osteoradionecrosis, its clinical and diagnostic particulars, prevention, and most widely accepted treatment options, as well as new possibilities relating to clinical management of the disorder. Lastly, a new early management protocol is proposed based on the current consensus criteria relating to maxillary osteonecrosis secondary to treatment with bisphosphonates, together with the adoption of new therapies supported by increased levels of evidence. © Medicina Oral S. L. es
dc.title Clinico-therapeutic management of osteoradionecrosis : a literature review and update es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.17257 es
dc.type.hasVersion VoR es_ES

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