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Antibacterial susceptibility patterns of porphyromonas gingivalis isolated from chronic periodontitis patients

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Antibacterial susceptibility patterns of porphyromonas gingivalis isolated from chronic periodontitis patients

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dc.contributor.author Japoni, Aziz es
dc.contributor.author Vazin, Afsaneh es
dc.contributor.author Noushadi, Sadighah es
dc.contributor.author Kiany, Farin es
dc.contributor.author Japoni, Sara es
dc.contributor.author Alborzi, Abdolvahab es
dc.date.accessioned 2017-07-26T08:27:12Z
dc.date.available 2017-07-26T08:27:12Z
dc.date.issued 2011 es
dc.identifier.citation Japoni, Aziz ; Vazin, Afsaneh ; Noushadi, Sadighah ; Kiany, Farin ; Japoni, Sara ; Alborzi, Abdolvahab. Antibacterial susceptibility patterns of porphyromonas gingivalis isolated from chronic periodontitis patients. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 16 7 2011: 29- es
dc.identifier.uri http://hdl.handle.net/10550/60062
dc.description.abstract Objectives: To test the antimicrobial sensitivity of Porphyromonas gingivalis to a panel of eight orally administrable antibiotics in chronic periodontal diseases and to evaluate factors associated with periodontitis in adult patients. Study Design: A total of fifty strains of P. gingivalis were isolated from one hundred and twenty adult patients with chronic perio-dontitis. Identification of bacteria was carried out by anaerobic culture and biochemical tests. Selected colonies of P. gingivalis were used to evaluate the antibacterial activities of penicillin, metronidazole, amoxicillin, amoxicillin/clavulanic acid, clindamycin, doxy-cycline, ciprofloxacin and azithromycin. Results: Most of the patients were female, age ranging between 40 to 50 years. Majority of the patients frequently had scaling and depths of periodontal pockets in infected teeth were 5-8 mm and most of them had hemorrhage during sampling. Susceptibility testing revealed a sensitivity of 100% of P. gingivalis to azithromycin, doxycycline and amoxicillin/clavulanic acid but lower susceptibilities were found for the rest of antibiotic agents evaluated. Conclusions: Frequent scaling in women aged between 40-50 years had positive correlation with chronic periodontitis. The application of antibiotics in conjuction with mechanical debridation, may reflect in the level of resistance of P. gingivalis in patients with chronic periodontal infections. This could suggest periodical antibiotic susceptibility testing is necessary to determine the efficacy of antimicrobial agents if the perfect curing of chronic periodontal diseases after mechanical debridation is meant. Further clinical studies are required to confirm the in vitro results. The only limitation in this study was identification of bacteria to species rather than subspecies level. © Medicina Oral S.L. es
dc.title Antibacterial susceptibility patterns of porphyromonas gingivalis isolated from chronic periodontitis patients es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.17174 es
dc.type.hasVersion VoR es_ES

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