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Merkel cell carcinoma : our experience in this rare pathology

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Merkel cell carcinoma : our experience in this rare pathology

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dc.contributor.author Rosado Rodríguez, Pablo es
dc.contributor.author Junquera Gutiérrez, Luis Manuel es
dc.contributor.author Vivanco Allende, B. es
dc.contributor.author García Consuegra, Luis es
dc.contributor.author Gallego, Lorena es
dc.date.accessioned 2017-07-26T10:36:17Z
dc.date.available 2017-07-26T10:36:17Z
dc.date.issued 2011 es
dc.identifier.citation Rosado Rodríguez, Pablo ; Junquera Gutiérrez, Luis Manuel ; Vivanco Allende, B. ; García Consuegra, Luis ; Gallego, Lorena. Merkel cell carcinoma : our experience in this rare pathology. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 16 6 2011: 8- es
dc.identifier.uri http://hdl.handle.net/10550/60094
dc.description.abstract Merkel cell carcinoma (MCC) was first described in 1972 by Toker, who described five cases of the so-called "trabecular carcinoma of the skin". MCC is a rare, aggressive skin cancer that affects mainly the elderly. Sun exposed areas are mainly affected, specially the head and neck. Immunohistochemical analysis is essential to reach a correct diagnosis. According to the origin of MCC, the tumor expresses both epithelial and neuroendocrine markers. MCC has a propensity for recurrence, regional and distant metastases. Several treatment options are available, such as surgical excision or Moh's surgery, accompanied by neck dissection or radio and chemotherapy in advanced cases. The present study aims to evaluate the clinical behaviour and the evolution of five cases of this disease that were treated at our institution (reference to 1100000 inhabitants) in the last five years. It is stressed on the bad prognosis of this pathology, which presents high rates of locoregional recurrence, even though the recent advances in radio and chemotherapy. © Medicina Oral S. L. es
dc.title Merkel cell carcinoma : our experience in this rare pathology es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.17068 es
dc.type.hasVersion VoR es_ES

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