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Oral contraceptive use and salivary C-erbB-2, CEA and CA15-3 in healthy women : a case-control study

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Oral contraceptive use and salivary C-erbB-2, CEA and CA15-3 in healthy women : a case-control study

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dc.contributor.author Vahedi, Mohammad es
dc.contributor.author Abdollahzadeh, Shermin es
dc.contributor.author Vaziri, Pejman Bakianian es
dc.contributor.author Mortazavi, Hamed es
dc.date.accessioned 2017-07-27T06:48:20Z
dc.date.available 2017-07-27T06:48:20Z
dc.date.issued 2011 es
dc.identifier.citation Vahedi, Mohammad ; Abdollahzadeh, Shermin ; Vaziri, Pejman Bakianian ; Mortazavi, Hamed. Oral contraceptive use and salivary C-erbB-2, CEA and CA15-3 in healthy women : a case-control study. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 16 1 2011: 7- es
dc.identifier.uri http://hdl.handle.net/10550/60193
dc.description.abstract Objectives: Oral contraceptives (OCP) are highly effective, safe and widely used. Higher exposure to endogenous and exogenous estrogens is generally thought to increase the risk of breast cancer. Therefore, this study was conducted to determine if oral contraceptive use affected the expression of CA 15-3, CEA and C-erb B-2 in the saliva of healthy women. Study design: The participants consisted of 87 healthy women (43 controls and 44 using oral contraceptives) ranging in age from 20 to 54 years. The volunteers participated by giving one ? time stimulated whole saliva samples. Then the samples were analysed for CA 15-3, CEA and C-erb B-2 concentrations. Results: The student t-test was used to compare group means for variables with comparable variability. The mean of C-erb B-2, CEA, and CA 15-3 concentrations (in the case and control groups) was (1.93, 1.70), (34.46, 31.62) and (12.58, 16.19) respectively. These differences were not statistically significant. Conclusions: Our findings suggest that the levels of the cancer biomarkers C-erb B-2, CEA and CA 15-3 were not affected by increased levels of estrogens in the body. es
dc.title Oral contraceptive use and salivary C-erbB-2, CEA and CA15-3 in healthy women : a case-control study es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.16.e29 es
dc.type.hasVersion VoR es_ES

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