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Analysis of familial incidence of non-syndromic cleft lip and palate in a Brazilian population

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Analysis of familial incidence of non-syndromic cleft lip and palate in a Brazilian population

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dc.contributor.author Martelli, Daniella Reis es
dc.contributor.author Bonan, Paulo Rogério Ferreti es
dc.contributor.author Soares, Matheus Carvalho es
dc.contributor.author Paranaíba, Lívia M. R. es
dc.contributor.author Martelli Júnior, Hercílio es
dc.date.accessioned 2017-07-27T06:50:14Z
dc.date.available 2017-07-27T06:50:14Z
dc.date.issued 2010 es
dc.identifier.citation Martelli, Daniella Reis ; Bonan, Paulo Rogério Ferreti ; Soares, Matheus Carvalho ; Paranaíba, Lívia M. R. ; Martelli Júnior, Hercílio. Analysis of familial incidence of non-syndromic cleft lip and palate in a Brazilian population. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 15 6 2010: 15- es
dc.identifier.uri http://hdl.handle.net/10550/60228
dc.description.abstract Background: The purpose of this study is to follow the familial incidence of non-syndromic or isolated cleft lip, with or without cleft palate (NSCL/P), and to analyze the relationships between the type of NSCL/P in the affected individual and his/her parent, looking at children in the first grade. Material and Methods: To investigate the familial incidence of NSCL/P we analyzed the records of 185 patients from 2004-2008, retrospectively. Detailed histories were collected regarding the familial incidence of NSCL/P. For the 185 individuals, the relationship between the type of NSCL/P and the sociodemographic and personal characteristics of the affected person and her/his cleft relatives was obtained. Results: The individuals were 42 carriers of CL, 109 with CLP (joined in one group) and 34 with CP (p<0.001). Of the total of participants, 65 (35.13%) presented a positive history of cleft in their families and 120 (64.86%) presented a negative history (p<0.001). There were differences between the cleft groups according to types of cleft and positive familial history (p<0.001). In both groups, the relatives with higher incidence of NSCL/P were cousins, with the same pattern of distribution between the two groups (p=0.175). Conclusions: Most frequently, fissures result from CL/CLP with no familial history. However, CL/CLP was found in familial cases and cousins were the relative type more likely to be affected. es
dc.title Analysis of familial incidence of non-syndromic cleft lip and palate in a Brazilian population es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.15.e898 es
dc.type.hasVersion VoR es_ES

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