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Mucositis in irradiated cancer patients : effects of an antiseptic mouthrinse

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Mucositis in irradiated cancer patients : effects of an antiseptic mouthrinse

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dc.contributor.author Lanzós, Isabel es
dc.contributor.author Herrera, David es
dc.contributor.author Santos, Sagrario es
dc.contributor.author O'Connor, Ana es
dc.contributor.author Peña, Carmen es
dc.contributor.author Lanzos González, Eduardo es
dc.contributor.author Sanz Alonso, Mariano es
dc.date.accessioned 2017-07-27T06:53:07Z
dc.date.available 2017-07-27T06:53:07Z
dc.date.issued 2010 es
dc.identifier.citation Lanzós, Isabel ; Herrera, David ; Santos, Sagrario ; O'Connor, Ana ; Peña, Carmen ; Lanzos González, Eduardo ; Sanz Alonso, Mariano. Mucositis in irradiated cancer patients : effects of an antiseptic mouthrinse. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 15 5 2010: 12- es
dc.identifier.uri http://hdl.handle.net/10550/60254
dc.description.abstract Objective: To assess the effects of an antiseptic, non-alcohol based mouth-rinse containing chlorhexidine and cetylpyridinium chloride, in preventing the oral complications associated to radiation therapy in head-and-neck cancer patients. Study design: This was a parallel, double blind, prospective, randomized clinical trial. Cancer patients were randomly assigned to one of the two treatments (test mouth-rinse or a placebo). Three visits were scheduled (baseline, 14 and 28 days). Different outcome variables were evaluated: mucositis, plaque and gingival indices, stimulated saliva and salivary pH. Results: 70 patients were screened and 36 were included. The presence and the degree of mucositis significantly increased in both groups and no significant differences were detected between groups, although the median increase in the placebo group (1.81) at 2 weeks was higher than in the test group (1.20). Conclusions: Within the limitations of the small sample size, this study suggests that the use of the tested mouthrinse may lead to some improvements in clinical parameters in patients irradiated for head-and-neck cancer. es
dc.title Mucositis in irradiated cancer patients : effects of an antiseptic mouthrinse es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.15.e732 es
dc.type.hasVersion VoR es_ES

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