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Assessment of salivary and serum antioxidant status in patients with recurrent aphthous stomatitis

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Assessment of salivary and serum antioxidant status in patients with recurrent aphthous stomatitis

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dc.contributor.author Momen Beitollahi, Jalil es
dc.contributor.author Mansourian, Arash es
dc.contributor.author Momen Heravi, Fatemeh es
dc.contributor.author Amanlou, Masoud es
dc.contributor.author Obradov, Stoyana es
dc.contributor.author SahebJamee, Mahnaz es
dc.date.accessioned 2017-07-27T06:54:57Z
dc.date.available 2017-07-27T06:54:57Z
dc.date.issued 2010 es
dc.identifier.citation Momen Beitollahi, Jalil ; Mansourian, Arash ; Momen Heravi, Fatemeh ; Amanlou, Masoud ; Obradov, Stoyana ; SahebJamee, Mahnaz. Assessment of salivary and serum antioxidant status in patients with recurrent aphthous stomatitis. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 15 4 2010: 3- es
dc.identifier.uri http://hdl.handle.net/10550/60274
dc.description.abstract Objective: The aim of this study was to determine the possible association of oxidant/antioxidant status and recurrent aphthous stomatitis (RAS). Study design: The study consis ted of thirty-one patients with RAS and thirty-two healthy controls from whom saliva and blood samples were collected. Superoxide dismutase (SOD), glutathione peroxidase (GSHPx) and catalase (CAT) were measured in erythrocytes and total antioxidant status (TAS) was measured in plasma and saliva. Results: Erythrocyte SOD activity was significantly lower in RAS patients in comparison to healthy controls (P=0.012). No significant differences were found in erythrocyte GSHPx, CAT activities, and salivary and plasma TAS between RAS patients and control subjects (p>0.1). Conclusion: Changes in SOD activity may be important in the inflammatory reactions observed in RAS, but other tested defense systems such as CAT and GSHPx do not seem to play a primary role in the aetiopathogenesis of RAS. Moreover, the antioxidant system in saliva and plasma is not as affected as in erythrocytes in RAS patients, and therefore it may not be considered an appropriate indicator of the body?s total antioxidant status. es
dc.title Assessment of salivary and serum antioxidant status in patients with recurrent aphthous stomatitis es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.15.e557 es
dc.type.hasVersion VoR es_ES

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