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Myofibroma of the oral cavity. A rare spindle cell neoplasm

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Myofibroma of the oral cavity. A rare spindle cell neoplasm

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dc.contributor.author Brasileiro, Bernardo Ferreira es
dc.contributor.author Martins Filho, Paulo R. es
dc.contributor.author Piva, Marta R. es
dc.contributor.author Silva, Luiz Carlos F. es
dc.contributor.author Nonaka, Cassiano-Francisco-Weege es
dc.contributor.author Miguel, Márcia Cristina da Costa es
dc.date.accessioned 2017-07-27T06:54:58Z
dc.date.available 2017-07-27T06:54:58Z
dc.date.issued 2010 es
dc.identifier.citation Brasileiro, Bernardo Ferreira ; Martins Filho, Paulo R. ; Piva, Marta R. ; Silva, Luiz Carlos F. ; Nonaka, Cassiano-Francisco-Weege ; Miguel, Márcia Cristina da Costa. Myofibroma of the oral cavity. A rare spindle cell neoplasm. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 15 4 2010: 10- es
dc.identifier.uri http://hdl.handle.net/10550/60281
dc.description.abstract Myofibroma is an uncommon spindle cell neoplasm rarely found in oral cavity. Typically, this lesion is seen in neonates and infants with few cases reported in adults patients. In the oral cavity, myofibroma occurs within the submucosal or intramuscular tissue and has a predilection by the tongue, buccal mucosa and lips. Microscopically, a typical biphasic pattern can be observed. Misdiagnosis included benign and malignant spindle cell lesions of nerve tissue or smooth muscle origin, such as neurofibroma, leiomyoma and sarcomas. Thus, immunohistochemical staining is a useful tool to identify the nature of neoplastic cells and to reach an accurate diagnosis. An immunohistochemical panel consisting of antibodies to vimentin, SMA, HHF-35, S-100p and desmin must be achieved. In most cases, positivity for vimentin, SMA and HHF-25 can be observed. Our report describes a solitary myofibroma of the tongue of a 23-year-old man with emphasis in clinical, histopathological and immunohistochemical features of this lesion. es
dc.title Myofibroma of the oral cavity. A rare spindle cell neoplasm es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.15.e596 es
dc.type.hasVersion VoR es_ES

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