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Efficacy and safety comparison of two amoxicillin administration schedules after third molar removal. A randomized, double-blind and controlled clinical trial

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Efficacy and safety comparison of two amoxicillin administration schedules after third molar removal. A randomized, double-blind and controlled clinical trial

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dc.contributor.author Luaces Rey, Ramón es
dc.contributor.author Arenaz Búa, Jorge es
dc.contributor.author López-Cedrún Cembranos, José Luis es
dc.contributor.author Martínez Roca, C. es
dc.contributor.author Pértega Díaz, Sonia es
dc.contributor.author Sironvalle Soliva, S. es
dc.date.accessioned 2017-07-27T06:56:53Z
dc.date.available 2017-07-27T06:56:53Z
dc.date.issued 2010 es
dc.identifier.citation Luaces Rey, Ramón ; Arenaz Búa, Jorge ; López-Cedrún Cembranos, José Luis ; Martínez Roca, C. ; Pértega Díaz, Sonia ; Sironvalle Soliva, S.. Efficacy and safety comparison of two amoxicillin administration schedules after third molar removal. A randomized, double-blind and controlled clinical trial. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 15 4 2010: 18- es
dc.identifier.uri http://hdl.handle.net/10550/60320
dc.description.abstract Objective: The aim of this comparative double-blind, prospective, randomized, clinical trial was to evaluate two amoxicillin administration patterns. The first was a short prophylactic therapy and the second a long postoperative regimen. Study Design: The study population consisted of 160 patients who underwent mandibular third molar extraction. Patients were randomized into two equal groups. In group 1, 2 grams of amoxicillin were administered 1 hour before the procedure and 1 gram 6 hours after surgery. In group 2, patients received 1 gram of amoxicillin 6 hours after surgery followed by 1 gram every 8 hour for 4 days. All patients received the same number of tablets thanks to the use of placebo pills. A total of 25 variables were evaluated, such as alveolitis, surgical infection, number of analgesic needed, subjective pain scale, post-surgical inflammation, consistency of the diet, axillary temperature and millimetres of mouth opening loss after the surgery. Results: No statistically significant post-operative differences were found within the recorded parameters between the groups. Conclusions: Postoperative 4-days amoxicillin therapy is not justified. es
dc.title Efficacy and safety comparison of two amoxicillin administration schedules after third molar removal. A randomized, double-blind and controlled clinical trial es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.15.e633 es
dc.type.hasVersion VoR es_ES

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