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The use of carrageenan for limiting the mandibular movement in rats : a preliminary experimental study

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The use of carrageenan for limiting the mandibular movement in rats : a preliminary experimental study

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dc.contributor.author Porto, Gabriela Granja es
dc.contributor.author Cavalcanti do Egito Vasconcelos, Belmiro es
dc.contributor.author Silva Junior, Valdemiro Amaro da es
dc.contributor.author Andrade, Emanuel Sávio de Sousa es
dc.date.accessioned 2017-07-27T06:56:54Z
dc.date.available 2017-07-27T06:56:54Z
dc.date.issued 2010 es
dc.identifier.citation Porto, Gabriela Granja ; Cavalcanti do Egito Vasconcelos, Belmiro ; Silva Junior, Valdemiro Amaro da ; Andrade, Emanuel Sávio de Sousa. The use of carrageenan for limiting the mandibular movement in rats : a preliminary experimental study. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 15 4 2010: 22- es
dc.identifier.uri http://hdl.handle.net/10550/60324
dc.description.abstract Purpose: The objective of this study was to evaluate if the carrageenan may be used for limiting the mandibular movement. Material and Methods: Eighteen adult male Wistar rats were used for the research, 20 µl of carrageenan (4%) was infiltrated in the extra articular region, in front of the condyle to induce fibrosis. The rats were divided into groups according to the time of euthanasia (7, 15 and 30 days). Maximal mouth opening (MMO), mandibular deviation, initial and final weights were recorded and evaluated. After the euthanasia, the specimens were submitted to histological study in order to classify the inflammatory process using scores. Results: The mean differences between initial and final MMO were 1.50 mm, being greatest at the 7 days evaluation and lowest at 30 days, and were not statistically significant at any time. No mandibular deviation was observed at any of the times of evaluation. The histological scores tended to increase with time of evaluation from 7 to 30 days, but without progression of the process. Conclusion: The study model permitted the development of fibrosis in the extra-articular region in the majority of the animals. es
dc.title The use of carrageenan for limiting the mandibular movement in rats : a preliminary experimental study es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.15.e653 es
dc.type.hasVersion VoR es_ES

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