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Molecular detection of Helicobacter pylori in oral samples from patients suffering digestive pathologies

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Molecular detection of Helicobacter pylori in oral samples from patients suffering digestive pathologies

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dc.contributor.author Medina, Myriam Lucrecia es
dc.contributor.author Medina, Marcelo Gabriel es
dc.contributor.author Martín, Graciela Teresita es
dc.contributor.author Picón, Santiago Omar es
dc.contributor.author Bancalari, Adriana es
dc.contributor.author Merino, Luis Antonio es
dc.date.accessioned 2017-07-27T08:46:23Z
dc.date.available 2017-07-27T08:46:23Z
dc.date.issued 2010 es
dc.identifier.citation Medina, Myriam Lucrecia ; Medina, Marcelo Gabriel ; Martín, Graciela Teresita ; Picón, Santiago Omar ; Bancalari, Adriana ; Merino, Luis Antonio. Molecular detection of Helicobacter pylori in oral samples from patients suffering digestive pathologies . En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 15 1 2010: 9- es
dc.identifier.uri http://hdl.handle.net/10550/60394
dc.description.abstract Objective: to determine the simultaneous presence of H. pylori in both the oral cavity and gastric mucosal in patients suffering digestive pathologies and to establish the possible association between the presence of H. pylori in the oral cavity and the gingivoperiodontal pathology. Study design: Patients with gastric symptoms (case group) and asymptomatic patients (control group) seen at the Gastroenterology Department of Dr. Julio C. Perrando Hospital (Resistencia, Argentina) were selected. Dental plaque and saliva samples from both groups were obtained. In the case group, gastric biopsy samples were also taken. H. pylori was detected in gastric biopsies by histological stains, and Polymerase Chain Reaction (PCR) was carried out on the oral samples. Results: Among the 98 patients (43 cases and 55 controls), 196 oral samples (saliva 98, dental plaque 98) and 43 gastric biopsias were obtained. H. pylori was detected in oral samples in 18/98 patients, in gastric biopsies in 38/43 patients, and in both samples in 15/43 patients. Conclusions: The presence of H. pylori in the oral cavity of patients suffering digestive pathologies is more frequent in those patients harbouring a gingivoperiodontal disease, and this fact could represent an obstacle for the eradication of the bacterium. At the same time, it could constitute a risk factor for gastrointestinal reinfection after treatment. es
dc.title Molecular detection of Helicobacter pylori in oral samples from patients suffering digestive pathologies es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.15.e38 es
dc.type.hasVersion VoR es_ES

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