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Oral manifestations as the first presenting sign of Crohn?s disease in a pediatric patient

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Oral manifestations as the first presenting sign of Crohn?s disease in a pediatric patient

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dc.contributor.author Eckel, Ashley es
dc.contributor.author Lee, Dale es
dc.contributor.author Deutsch, Gail es
dc.contributor.author Maxin, Anthony es
dc.contributor.author Oda, Dolphine es
dc.date.accessioned 2017-09-28T11:29:34Z
dc.date.available 2017-09-28T11:29:34Z
dc.date.issued 2017 es
dc.identifier.citation Eckel, Ashley ; Lee, Dale ; Deutsch, Gail ; Maxin, Anthony ; Oda, Dolphine. Oral manifestations as the first presenting sign of Crohn?s disease in a pediatric patient. En: Journal of Clinical and Experimental Dentistry, 9 7 2017: 934-938 es
dc.identifier.uri http://hdl.handle.net/10550/61253
dc.description.abstract Crohn?s disease (CD) is a chronic inflammatory disorder affecting the gastrointestinal (GI) tract. Although the GI tract is the primary site of involvement, many patients, particularly in pediatric cases, first present with non-intestinal manifestations, including oral lesions. Oral manifestations of CD in children occur in around 50-80% of cases, and about 30% of CD cases in children occur first in the mouth. Recognizing such oral lesions in the pediatric population, and requesting a biopsy, may expedite the diagnosis of CD. We describe a 15 year old male who presented with oral findings of multiple aphthous ulcers and plaques of pink papules of the buccal vestibule. We highlight the initial pathology findings, including non-caseating granulomas, sialadenitis, and a notable plasmacytosis, from biopsy of the left retromolar pad area, which triggered further testing for CD. We provide discussion of how CD was eventually diagnosed and treated and highlight the significance of the pathological findings in this case as they relate to the pathogenesis of CD. es
dc.title Oral manifestations as the first presenting sign of Crohn?s disease in a pediatric patient es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.53914 es
dc.type.hasVersion VoR es_ES

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