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Relationship of salivary CD14 concentration with dental caries in young children

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Relationship of salivary CD14 concentration with dental caries in young children

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dc.contributor.author Kumar, Saurabh es
dc.contributor.author Tandon, Shobha es
dc.contributor.author Nayak, Rashmi es
dc.contributor.author Saran, Runki es
dc.contributor.author Pentapati, Kalyana-Chakravarty es
dc.date.accessioned 2017-11-15T09:24:27Z
dc.date.available 2017-11-15T09:24:27Z
dc.date.issued 2017 es
dc.identifier.citation Kumar, Saurabh ; Tandon, Shobha ; Nayak, Rashmi ; Saran, Runki ; Pentapati, Kalyana-Chakravarty. Relationship of salivary CD14 concentration with dental caries in young children. En: Journal of Clinical and Experimental Dentistry, 9 8 2017: 958-961 es
dc.identifier.uri http://hdl.handle.net/10550/63048
dc.description.abstract Dental caries is a chronic disease among children and there is need for studies assessing the caries risk factors using saliva. This study aimed to evaluate the association of salivary soluble CD14 and dental caries in young children. A cross-sectional study was done among 300, 3-6 year old school children of Udupi district. A total of 40 children who were caries free, with no past systemic illness or craniofacial anomalies and 40 children with dental caries with no history of dental treatment for caries, with no past systemic illness or craniofacial anomalies were included in control and test groups respectively. Salivary CD14 was evaluated using ELISA test. The mean salivary soluble CD14 concentration was significantly higher in caries free (1.34±0.35 µg/ml) children than caries experienced (0.54±0.36 µg/ml) (p<0.001). There was significant strong negative correlation between number of decayed teeth and soluble salivary CD14 (r = -0.868, P< 0.001) among all the children. Similarly, sub-group analysis of caries experienced children also showed significant strong negative correlation between number of decayed teeth and soluble salivary CD14 (r = -0.774, P<0.001). Results obtained in our study suggested that salivary CD14 can be a indicator of dental caries in young children. es
dc.title Relationship of salivary CD14 concentration with dental caries in young children es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.53796 es
dc.type.hasVersion VoR es_ES

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