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High resolution image in bone biology I : review of the literature

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High resolution image in bone biology I : review of the literature

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Cano Sánchez, Jorge; Campo Trapero, Julián; Vaquero, Juan José; Martínez González, José María; Bascones Martínez, Antonio
Aquest document és un/a article, creat/da en: 2007

Bone microstructure has usually been assessed by obtaining samples invasively and analyzing them with conventional histomorphometric methods. Improvements in high-resolution image acquisition systems have enabled non-invasive assessment of bone morphology and a more precise 3-D evaluation by means of ?virtual biopsies?, permitting bone assessment in regeneration or remodeling processes. This review describes the characteristics and limitations of bone assessment using different high-resolution image systems (synchrotron-radiation computed tomography, micro-computed tomography, acoustic scanning microscope; micro-magnetic resonance imaging). Morphometric variables that can be obtained from these images are reported and compared with conventional histomorphometric variables.
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