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Metastatic neuroblastoma to the mandible in a 3-year-old boy : a case report

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Metastatic neuroblastoma to the mandible in a 3-year-old boy : a case report

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dc.contributor.author Otmani, Naima es
dc.contributor.author Khattab, Mohamed es
dc.date.accessioned 2017-11-22T09:29:37Z
dc.date.available 2017-11-22T09:29:37Z
dc.date.issued 2007 es
dc.identifier.citation Otmani, Naima ; Khattab, Mohamed. Metastatic neuroblastoma to the mandible in a 3-year-old boy : a case report. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 12 3 2007: 5- es
dc.identifier.uri http://hdl.handle.net/10550/63234
dc.description.abstract Although neuroblastoma is a relatively common malignancy of childhood and its dissemination to distant organs is often seen, metastasis to the mandible is rare. A 3-year-old boy which a mandibular soft tissue mass was the initial presenting symptom of disseminated neuroblastoma is reported. The results of biopsy were inconclusive and the differential diagnosis from the imaging studies included lymphoma, soft tissue sarcoma, and osteosarcoma. A metastatic work-up disclosed neuroblastoma of the adrenal gland origin with osseous and bone marrow metastases. Urinary catecolamines were also increased. Regarding the widespread features of the tumor and lack of adequate treatment at this stage of disease, a palliative chemotherapy was conducted, and the patient died one month after starting treatment. This case illustrates that neuroblastoma at a young age, with bone metastases and bone marrow involvement are predictive of the poor outcome of the disease. Therefore, detecting early stage metastasis is one of the essential factors for improving treatment of neuroblastoma patients. es
dc.title Metastatic neuroblastoma to the mandible in a 3-year-old boy : a case report es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi es
dc.type.hasVersion VoR es_ES

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