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Control of Frey?s syndrome in patients treated with botulinum toxin type A

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Control of Frey?s syndrome in patients treated with botulinum toxin type A

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dc.contributor.author Luna Ortiz, Kuauhyama es
dc.contributor.author Rascon Ortiz, Mario es
dc.contributor.author Sansón Riofrio, Jesús A. es
dc.contributor.author Villavicencio Valencia, Verónica es
dc.contributor.author Mosqueda Taylor, Adalberto es
dc.date.accessioned 2017-11-24T08:34:42Z
dc.date.available 2017-11-24T08:34:42Z
dc.date.issued 2007 es
dc.identifier.citation Luna Ortiz, Kuauhyama ; Rascon Ortiz, Mario ; Sansón Riofrio, Jesús A. ; Villavicencio Valencia, Verónica ; Mosqueda Taylor, Adalberto. Control of Frey?s syndrome in patients treated with botulinum toxin type A. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 12 1 2007: 18- es
dc.identifier.uri http://hdl.handle.net/10550/63304
dc.description.abstract Aim: To identify the severity of Frey?s syndrome and its response to botulinum toxin type A. Methods: Minor test was performed in all cases to assess the extent of the affected area, using the contralateral side as control. Severity was assessed according to the proposal of Luna-Ortiz et al. Response was evaluated after 3 and 6 months, and was compared with the basal data. Results: Frey?s syndrome was documented in 38 patients, but only 23 cases accepted the botulinum toxin type A treatment. Severity was moderate in 8 (35%) and severe in 15 (65%) cases. Mean applied dose was 1.41 MU/cm2 in 21 patients (91%), whereas one patient was treated with 10 MU for a 0.8 cm2 affected area (12.5 MU/cm2 ) and another patient with 10 MU for a 0.5 cm2 affected area (20 MU/cm2 ) due to severity of their symptomatology. Average affected area at the beginning was 14.2 cm2 , while after 3 and 6 months of treatment it was 4.1 cm2 and 4.4 cm2 respectively (p<0.001). The two patients that received higher doses of botulinum toxin A had complete response. Complete response was observed in 13 patients (56.5%) at 3 months, but in only nine (39%) this lack of symptomatology persisted at 6 months. In three cases (13%) no response was obtained at 3 months, and the application of an additional dose of botulinum toxin type A produced no response in two of them after 6 months. Comparison of the severity score of the average basal value vs. that obtained at 3 and 6 months revealed a significant difference (p< 0.05); however, no statistically significant difference was found when comparing outcome at 3 vs. 6 months. There were no statistically significant differences using the independent samples test when comparing outcome after treatment in relation to gender, type of surgery, or use of postoperative radiation therapy (p>0.05). In conclusion, botulinum toxin A remains as the treatment of choice for Frey?s syndrome. es
dc.title Control of Frey?s syndrome in patients treated with botulinum toxin type A es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi es
dc.type.hasVersion VoR es_ES

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