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Bisphosphonates and Oral Pathology II. Osteonecrosis of the jaws : Review of the literature before 2005

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Bisphosphonates and Oral Pathology II. Osteonecrosis of the jaws : Review of the literature before 2005

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dc.contributor.author Estefanía Fresco, Ruth es
dc.contributor.author Ponte Fernández, N. es
dc.contributor.author Aguirre Urízar, José Manuel es
dc.date.accessioned 2017-11-25T12:40:12Z
dc.date.available 2017-11-25T12:40:12Z
dc.date.issued 2006 es
dc.identifier.citation Estefanía Fresco, Ruth ; Ponte Fernández, N. ; Aguirre Urízar, José Manuel. Bisphosphonates and Oral Pathology II. Osteonecrosis of the jaws : Review of the literature before 2005. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 11 6 2006: 1- es
dc.identifier.uri http://hdl.handle.net/10550/63305
dc.description.abstract Bisphosphonates are bone-turnover modulating drugs which are used in the management of a number of bone diseases ranging from osteoporosis to neoplasic pathology-associated osteolysis. In the last years a number of cases of osteonecrosis of the jaws associated with these drugs have been reported. In this review we analyze the cases published in the literature indexed from 2003 to December 2005. During this period 246 cases were reported, being more frequently associated with women in the sixth decade of life. More frequently associated bisphosphonates were the nitrogenated bisphosphonates (pamidronate, zolendronic acid) and the most common oral antecedent was a dental extraction. Nevertheless more than 25% of the cases were spontaneous. The most frequent site was the mandible and most of the cases presented clinical evidence of bone exposure and pain. Different treatments have been proposed with different antibiotic therapies with or without surgery, showing in general terms an uncertain prognosis with low healing rates. es
dc.title Bisphosphonates and Oral Pathology II. Osteonecrosis of the jaws : Review of the literature before 2005 es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi es
dc.type.hasVersion VoR es_ES

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