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Amlodipine-induced gingival hyperplasia

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Amlodipine-induced gingival hyperplasia

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dc.contributor.author Lafzi, Ardeshir es
dc.contributor.author Farahani, Ramin Mostofi Zadeh es
dc.contributor.author Shoja, Mohammadali Mohajel es
dc.date.accessioned 2017-11-25T13:00:30Z
dc.date.available 2017-11-25T13:00:30Z
dc.date.issued 2006 es
dc.identifier.citation Lafzi, Ardeshir ; Farahani, Ramin Mostofi Zadeh ; Shoja, Mohammadali Mohajel. Amlodipine-induced gingival hyperplasia. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 11 6 2006: 5- es
dc.identifier.uri http://hdl.handle.net/10550/63309
dc.description.abstract Drug-induced gingival hyperplasia is a serious concern both for the patient and the clinician. A 45 year-old Caucasian male patient with hypertension, who received amlodipine (10 mg/day, single dose orally) for two months, sought medical attention because of the new-onset gingival enlargement. On clinical examination a generalized and firm overgrowth of the gingival throughout the maxilla and the mandible were evident. The lack of gingival inflammation and purulent discharge were other features of the clinical scenario. Histological assessment of the biopsy specimen revealed the hyperplasia of connective tissue, epithelial acanthosis, and elongated rete ridges along with few inflammatory cells. The histological and the clinical evidences were consistent with amlodipine-induced gingival hyperplasia. We believe that the present report indicates the most rapidly developed case of amlodipine-induced gingival hyperplasia reported to date. The related literature is reviewed and the underlying pathogenic mechanisms of this rare side-effect are discussed here. es
dc.title Amlodipine-induced gingival hyperplasia es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi es
dc.type.hasVersion VoR es_ES

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