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Qualitative and quantitative exfoliative cytology of normal oral mucosa in type 2 diabetic patients

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Qualitative and quantitative exfoliative cytology of normal oral mucosa in type 2 diabetic patients

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dc.contributor.author Shareef, Ban Tawfeek es
dc.contributor.author Ang, Kok Teong es
dc.contributor.author Naik, Venkatesh Ramasamy es
dc.date.accessioned 2017-12-16T08:25:40Z
dc.date.available 2017-12-16T08:25:40Z
dc.date.issued 2008 es
dc.identifier.citation Shareef, Ban Tawfeek ; Ang, Kok Teong ; Naik, Venkatesh Ramasamy. Qualitative and quantitative exfoliative cytology of normal oral mucosa in type 2 diabetic patients. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 13 11 2008: 4- es
dc.identifier.uri http://hdl.handle.net/10550/63637
dc.description.abstract Objective: The main purpose of this study is to emphasize the relevance of exfoliative cytology as an additional tool to aid in the diagnosis of diabetes mellitus. Materials and Methods: This is a comparative cross-sectional study. Oral smears were obtained from 10 diabetic patients and 10 healthy individuals. These smears were stained with Papanicolaou stain. The nuclear (NA) and cytoplasmic (CA) areas of 20 integral cells predominant in the buccal mucosa were measured using the Leica Qwin Version 2.1 image analysis system (LEICA GMBH GERMANY).The cytoplasmic/nuclear ratio (C/N) was then calculated. For comparing cytomorphometric parameters (NA, CA and C/N ratio) the Mann-Whitney test was used. Significance was set at P ? 0.05. Results: The morphologic alterations seen in buccal mucosal epithelial cells of the diabetic group were nuclear enlargement, karyorrhexis, binucleation and infiltration of polymorphonuclear leukocytes. The NA was significantly higher (P < 0.05) in the diabetic group. The CA between these two groups were not significantly different (P > 0.05). The C/N mean was significantly lower (P < 0.05) in the diabetic group. Conclusion: Exfoliative cytology is useful as an additional tool to aid in the diagnosis of diabetes mellitus es
dc.title Qualitative and quantitative exfoliative cytology of normal oral mucosa in type 2 diabetic patients es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi es
dc.type.hasVersion VoR es_ES

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