NAGIOS: RODERIC FUNCIONANDO

Interactions between ibuprofen and antihypertensive drugs : Incidence and clinical relevance in dental practice

Repositori DSpace/Manakin

IMPORTANT: Aquest repositori està en una versió antiga des del 3/12/2023. La nova instal.lació está en https://roderic.uv.es/

Interactions between ibuprofen and antihypertensive drugs : Incidence and clinical relevance in dental practice

Mostra el registre parcial de l'element

dc.contributor.author Salort Llorca, Cesar es
dc.contributor.author Mínguez Serra, María Paz es
dc.contributor.author Silvestre Donat, Francisco Javier es
dc.date.accessioned 2017-12-16T08:26:04Z
dc.date.available 2017-12-16T08:26:04Z
dc.date.issued 2008 es
dc.identifier.citation Salort Llorca, Cesar ; Mínguez Serra, María Paz ; Silvestre Donat, Francisco Javier. Interactions between ibuprofen and antihypertensive drugs : Incidence and clinical relevance in dental practice. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 13 11 2008: 9- es
dc.identifier.uri http://hdl.handle.net/10550/63642
dc.description.abstract It has been well documented in the literature that ibuprofen interacts with different groups of antihypertensive drugs (beta-adrenergic blockers, alpha-adrenergic blockers, diuretics and angiotensin-converting enzyme inhibitors), reducing their antihypertensive activity. The mechanism of action of ibuprofen involves inhibition of the enzyme cyclooxygenase, thereby inhibiting the synthesis of inflammatory prostaglandins and vasodilatory prostaglandins that increase renal blood flow and thus favor the excretion of water and sodium. More than five days of treatment with both drugs are normally required for the interaction to manifest. Although the changes in blood pressure resulting from this interaction are typically small, some patients can experience substantial elevations in both systolic and diastolic blood pressure. It has been estimated that the avoidance of minor changes in systolic pressure in patients with osteoarthritis subjected to treatment with nonsteroidal antiinflammatory drugs would avoid over 30,000 deaths due to myocardial infarction, and over 2000 deaths due to coronary disease, in the United States alone. es
dc.title Interactions between ibuprofen and antihypertensive drugs : Incidence and clinical relevance in dental practice es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi es
dc.type.hasVersion VoR es_ES

Visualització       (383.6Kb)

Aquest element apareix en la col·lecció o col·leccions següent(s)

Mostra el registre parcial de l'element

Cerca a RODERIC

Cerca avançada

Visualitza

Estadístiques