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Comparison of total antioxidant capacity of saliva in women with gestational diabetes mellitus and non-diabetic pregnant women

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Comparison of total antioxidant capacity of saliva in women with gestational diabetes mellitus and non-diabetic pregnant women

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dc.contributor.author Zamani-Ahari, Ulduz es
dc.contributor.author Zamani-Ahari, Sahar es
dc.contributor.author Fardi-Azar, Zahra es
dc.contributor.author Falsafi, Parisa es
dc.contributor.author Ghanizadeh, Milad es
dc.date.accessioned 2018-02-28T11:26:53Z
dc.date.available 2018-02-28T11:26:53Z
dc.date.issued 2017 es
dc.identifier.citation Zamani-Ahari, Ulduz ; Zamani-Ahari, Sahar ; Fardi-Azar, Zahra ; Falsafi, Parisa ; Ghanizadeh, Milad. Comparison of total antioxidant capacity of saliva in women with gestational diabetes mellitus and non-diabetic pregnant women. En: Journal of Clinical and Experimental Dentistry, 9 11 2017: 1282-1286 es
dc.identifier.uri http://hdl.handle.net/10550/65065
dc.description.abstract Pregnancy is considered a stressful event, results in higher levels of oxidative stress and considerable changes in physiological and metabolic functions such as gestational diabetes mellitus (GDM). Due to the cumulative effect of antioxidants and considering the controversies in this area, this study was undertaken to investigate the total antioxidant capacity (TAC) of saliva in pregnant women whit gestational diabetes in comparison to non-diabetic pregnant women. In this cross-sectional study (2015-16), a total of 31 women with a diagnosis of GDM and 59 non-diabetic pregnant women were included in the diabetic and control groups, respectively. Salivary samples were collected by spitting method. When all samples were collected, total antioxidant capacity (TAC) was measured with the use of a commercial kit following the manufacturer?s instructions. Data were analyzed with descriptive statistics and Mann-Whitney test using SPSS 18. Average TAC level in the saliva of women with gestational diabetes was 0.10 ± 0.14, with 0.04 ± 0.11 in non-diabetic pregnant women. Nonparametric Mann-Whitney test showed that this difference was statistically significant (P=0.024). Under the limitations of the present study it can be concluded that there is an increase in oxidative stresses during pregnancy, followed by an increase in the total levels of salivary antioxidants to counteract such stresses. Therefore, it is expected that determining the salivary antioxidant levels during pregnancy can be an alternative technique for the early diagnosis of diabetes. es
dc.title Comparison of total antioxidant capacity of saliva in women with gestational diabetes mellitus and non-diabetic pregnant women es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.53845 es
dc.type.hasVersion VoR es_ES

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