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Direct oral anticoagulants and its implications in dentistry : a review of literature

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Direct oral anticoagulants and its implications in dentistry : a review of literature

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dc.contributor.author Lanau, Neus es
dc.contributor.author Mareque Bueno, Javier es
dc.contributor.author Giner Tarrida, Lluís es
dc.contributor.author Zabalza, Michel es
dc.date.accessioned 2018-02-28T11:26:55Z
dc.date.available 2018-02-28T11:26:55Z
dc.date.issued 2017 es
dc.identifier.citation Lanau, Neus ; Mareque Bueno, Javier ; Giner Tarrida, Lluís ; Zabalza, Michel. Direct oral anticoagulants and its implications in dentistry : a review of literature. En: Journal of Clinical and Experimental Dentistry, 9 11 2017: 1346-1354 es
dc.identifier.uri http://hdl.handle.net/10550/65075
dc.description.abstract Four novel direct oral anticoagulants (DOACs) named dabigatran, rivaroxaban, edoxaban and apixaban have been recently introduced to overcome some of the drawbacks of existing anticoagulants. They have less interactions and do not require routine monitoring. However, there is not enough scientific data about the protocol to apply in these patients on DOACs undergoing dental treatment. Thus is necessary to evaluate the potential bleeding risk of these drugs, the possibility of thromboembolic events occurring if they are withdrawn or the need to change to heparin previously. A comprehensive search of the PubMed, Scopus and ISI Web of Science databases was conducted to identify studies that evaluated the relationship between direct oral anticoagulants and dental procedures. The quality of the reported information was assessed following the PRISMA statement. Eleven studies that met the inclusion criteria were included in the review: 2 randomized clinical trials, 3 prospective studies, 3 retrospective studies, 2 case series and 1 case report. DOACs are safe drugs in terms of bleeding. The possible postoperative bleeding complications are manageable with conventional haemostasis measurements. The bridging approach with heparin does not seem to be recommended. Consensus among the professionals involved in the management of the patient is fundamental in invasive dental treatments and in complex patients. es
dc.title Direct oral anticoagulants and its implications in dentistry : a review of literature es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.54004 es
dc.type.hasVersion VoR es_ES

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