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Pigmented squamous cell carcinoma in situ : report of a new case and review of the literature

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Pigmented squamous cell carcinoma in situ : report of a new case and review of the literature

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Martins, Fabiana; Mistro, Florence; Kignel, Sergio; Palmieri, Michelle; do Canto, Alan-Motta; Braz Silva, Paulo Henrique
Aquest document és un/a article, creat/da en: 2017

Pigmented squamous cell carcinoma in situ (PSCCIS) is very rare, being clinically described as a pigmented lesion with histological characteristics of an in-situ carcinoma presenting pigmentation within neoplastic cells. A 50-year-old Afro-descendant man came for clinical evaluation of a painful black and red lesion located on the right aspect of the oropharyngeal isthmus. After incisional biopsy, the resulting sample was described as a pigmented squamous cell carcinoma in situ, a diagnosis further confirmed by immunohistochemical analysis. Treatment consisted in total excision of the lesion, and no recurrence was observed after a 30-month follow-up. Clinicians and pathologists should be aware of PSCCIS as a differential diagnosis of melanoma, a lesion which significantly increases the morbidity and mortality rates among these patients.
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