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Sympathetic neural activity, metabolic parameters and cardiorespiratory fitness in obese youths.

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Sympathetic neural activity, metabolic parameters and cardiorespiratory fitness in obese youths.

dc.contributor.author	Redón, Pau
dc.contributor.author	Grassi, Guido
dc.contributor.author	Redón i Más, Josep
dc.contributor.author	Álvarez Pitti, Julio Carlos
dc.contributor.author	Lurbe i Ferrer, Empar
dc.date.accessioned	2018-04-10T11:08:36Z
dc.date.available	2018-04-10T11:08:36Z
dc.date.issued	2017
dc.identifier.citation	Redón, Pau Grassi, Guido Redón i Más, Josep Álvarez Pitti, Julio Carlos Lurbe i Ferrer, Empar 2017 Sympathetic neural activity, metabolic parameters and cardiorespiratory fitness in obese youths. Journal of Hypertension 35 3 571 577
dc.identifier.uri	http://hdl.handle.net/10550/65540
dc.description.abstract	OBJECTIVE: The main objective of this cross-sectional study is to assess the cardiac autonomic neural activity in the presence of abnormally increased body weight in youths and its relationship to metabolic risk factors and cardiorespiratory fitness (CRF). METHODS: Sixty-four overweight and obese patients, aged 9-17 years, of both sexes, stratified according to the international BMI cut-off, were enrolled. Continuous ECG was recorded during 15 min in resting conditions, and the heart rate variability (HRV) was measured in the time domain, frequency domain and for nonlinear dynamics. In addition, cardiometabolic risk factors and CRF in effort conditions were assessed. RESULTS: Among the overweight and obese youths, no significant differences were observed regarding metabolic parameters and heart rate, although CRF was the lowest in the severely obese youths. Likewise, no significant differences were observed in HRV, independent of how it was assessed. A positive and significant relationship, independent of the degree of obesity, pubertal stage and breathing rate under resting conditions, has been observed among sympathovagal balance, insulin and the homeostatic model assessment index. Furthermore, CRF assessed by volume oxygen peak was associated with insulin levels (r = -0.273; P < 0.05), the SD of the NN interval series (r = 0.268, P < 0.05) and the long-term variation using the Poincaré plot (PS1: r = 0.275, P < 0.05; PS2: r = 0.273, P < 0.05). CONCLUSION: The key findings of the present study were the presence of a link among fasting insulin, HRV and CRF independent of the degree of obesity, indicating the heterogeneity of obese children and adolescents.
dc.language.iso	eng
dc.relation.ispartof	Journal of Hypertension, 2017, vol. 35, num. 3, p. 571-577
dc.subject	Obesitat
dc.subject	Adolescents
dc.subject	Sistema cardiovascular
dc.title	Sympathetic neural activity, metabolic parameters and cardiorespiratory fitness in obese youths.
dc.type	journal article	es_ES
dc.date.updated	2018-04-10T11:08:36Z
dc.identifier.doi	10.1097/HJH.0000000000001200
dc.identifier.idgrec	115202
dc.rights.accessRights	open access	es_ES