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FIMic: design for ultimate 3D-integral microscopy of in-vivo biological samples

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FIMic: design for ultimate 3D-integral microscopy of in-vivo biological samples

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dc.contributor.author	Scrofani, G.
dc.contributor.author	Sola Pikabea, Jorge
dc.contributor.author	Llavador Ancheta, Ana Isabel
dc.contributor.author	Sánchez Ortiga, Emilio
dc.contributor.author	Barreiro Hervás, Juan Carlos
dc.contributor.author	Saavedra Tortosa, Genaro
dc.contributor.author	García Sucerquia, Jorge Iván
dc.contributor.author	Martínez Corral, Manuel
dc.date.accessioned	2018-04-10T12:53:43Z
dc.date.available	2018-04-10T12:53:43Z
dc.date.issued	2018
dc.identifier.citation	Scrofani, G. Sola-Pikabea, J. Llavador Ancheta, Ana Isabel Sánchez Ortiga, Emilio Barreiro Hervás, Juan Carlos Saavedra Tortosa, Genaro García Sucerquia, Jorge Iván Martínez Corral, Manuel 2018 FIMic: design for ultimate 3D-integral microscopy of in-vivo biological samples Biomedical Optics Express 9 1 335 346
dc.identifier.uri	http://hdl.handle.net/10550/65555
dc.description.abstract	In this work, Fourier integral microscope (FIMic), an ultimate design of 3D-integral microscopy, is presented. By placing a multiplexing microlens array at the aperture stop of the microscope objective of the host microscope, FIMic shows extended depth of field and enhanced lateral resolution in comparison with regular integral microscopy. As FIMic directly produces a set of orthographic views of the 3D-micrometer-sized sample, it is suitable for real-time imaging. Following regular integral-imaging reconstruction algorithms, a 2.75-fold enhanced depth of field and √2-time better spatial resolution in comparison with conventional integral microscopy is reported. Our claims are supported by theoretical analysis and experimental images of a resolution test target, cotton fibers, and in-vivo 3D-imaging of biological specimens.
dc.language.iso	eng
dc.relation.ispartof	Biomedical Optics Express, 2018, vol. 9, num. 1, p. 335-346
dc.subject	Imatges tridimensionals en biologia
dc.subject	Microscòpia
dc.subject	Òptica
dc.title	FIMic: design for ultimate 3D-integral microscopy of in-vivo biological samples
dc.type	journal article	es_ES
dc.date.updated	2018-04-10T12:53:44Z
dc.identifier.doi	10.1364/BOE.9.000335
dc.identifier.idgrec	124409
dc.rights.accessRights	open access	es_ES