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The assessment of surgical and non-surgical treatment of stage II medication-related osteonecrosis of the jaw

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The assessment of surgical and non-surgical treatment of stage II medication-related osteonecrosis of the jaw

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dc.contributor.author Eguchi, Takanori es
dc.contributor.author Kanai, Ikuyo es
dc.contributor.author Basugi, Akihiko es
dc.contributor.author Miyata, Yukinaga es
dc.contributor.author Inoue, Minako es
dc.contributor.author Hamada, Yoshiki es
dc.date.accessioned 2018-05-02T12:04:12Z
dc.date.available 2018-05-02T12:04:12Z
dc.date.issued 2017 es
dc.identifier.citation Eguchi, Takanori ; Kanai, Ikuyo ; Basugi, Akihiko ; Miyata, Yukinaga ; Inoue, Minako ; Hamada, Yoshiki. The assessment of surgical and non-surgical treatment of stage II medication-related osteonecrosis of the jaw. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 22 6 2017: 17- es
dc.identifier.uri http://hdl.handle.net/10550/65949
dc.description.abstract Non-surgical treatment has generally been recommended for stage II medication-related osteonecrosis of the jaw (MRONJ) in preference to surgery. However, non-surgical treatment is not empirically effective. The aim of this study was to evaluate whether surgical or non-surgical treatment leads to better outcomes for stage II MRONJ. In this retrospective study, surgery was performed in a total of 28 patients while 24 patients underwent non-surgical treatment. The outcomes of both treatment approaches after 6 months were evaluated and statistically compared. In addition, risk factors for surgical and non-surgical treatments were assessed for each. Surgical treatment in 25 patients (89.3%) resulted in success, with failure in 3 patients (10.7%). Non-surgical treatment was successful for 8 patients (33.3%) and failed in 16 patients (66.7%). There was therefore a significant difference between surgical and non-surgical treatment outcomes (P<0.01). Regarding risk factors, in non-surgical treatment primary diseases, medications, and drug holiday had a significant effect on outcomes (P<0.01). Risk factors for surgical treatment could not be clarified. Surgical treatment is more effective than non-surgical treatment for stage II MRONJ, and drug holiday, primary disease, and medication constitute risk factors in non-surgical treatment. es
dc.title The assessment of surgical and non-surgical treatment of stage II medication-related osteonecrosis of the jaw es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.22013 es
dc.type.hasVersion VoR es_ES

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