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Oral cancer associated with chronic mechanical irritation of the oral mucosa

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Oral cancer associated with chronic mechanical irritation of the oral mucosa

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dc.contributor.author Piemonte, Eduardo es
dc.contributor.author Lazos, Jerónimo es
dc.contributor.author Belardinelli, Paola es
dc.contributor.author Secchi, Dante Gustavo es
dc.contributor.author Brunotto, Mabel es
dc.contributor.author Lanfranchi, Héctor es
dc.date.accessioned 2018-05-23T08:27:54Z
dc.date.available 2018-05-23T08:27:54Z
dc.date.issued 2018 es
dc.identifier.citation Piemonte, Eduardo ; Lazos, Jerónimo ; Belardinelli, Paola ; Secchi, Dante Gustavo ; Brunotto, Mabel ; Lanfranchi, Héctor. Oral cancer associated with chronic mechanical irritation of the oral mucosa. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 23 2 2018: 6- es
dc.identifier.uri http://hdl.handle.net/10550/66304
dc.description.abstract Most of the studies dealing with Chronic Mechanical Irritation (CMI) and Oral Cancer (OC) only considered prosthetic and dental variables separately, and CMI functional factors are not registered. Thus, the aim of this study was to assess OC risk in individuals with dental, prosthetic and functional CMI. Also, we examined CMI presence in relation to tumor size. A case-control study was carried out from 2009 to 2013. Study group were squamous cell carcinoma cases; control group was patients seeking dental treatment in the same institution. 153 patients were studied (Study group n=53, Control group n=100). CMI reproducibility displayed a correlation coefficient of 1 (p<0.0001). Bivariate analysis showed statistically significant associations for all variables (age, gender, tobacco and alcohol consumption and CMI). Multivariate analysis exhibited statistical significance for age, alcohol, and CMI, but not for gender or tobacco. Relationship of CMI with tumor size showed no statistically significant differences. CMI could be regarded as a risk factor for oral cancer. In individuals with other OC risk factors, proper treatment of the mechanical injuring factors (dental, prosthetic and functional) could be an important measure to reduce the risk of oral cancer. es
dc.title Oral cancer associated with chronic mechanical irritation of the oral mucosa es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.22017 es
dc.type.hasVersion VoR es_ES

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