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Impact of the anatomical location, alcoholism and smoking on the prevalence of advanced oral cancer in Brazil

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Impact of the anatomical location, alcoholism and smoking on the prevalence of advanced oral cancer in Brazil

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dc.contributor.author Bezerra, Natanael-Victor-Furtunato es
dc.contributor.author Leite, Karla-Lorene-de França es
dc.contributor.author de Medeiros, Mariana-Marinho-Davino es
dc.contributor.author Martins, Mariana-Leonel es
dc.contributor.author Cardoso, Andrea-Medeiros-Rodrigues es
dc.contributor.author Alves, Pollianna-Muniz es
dc.contributor.author Padilha, Wilton-Wilney-Nascimento es
dc.contributor.author Cavalcanti, Yuri-Wanderley es
dc.date.accessioned 2018-05-28T10:45:22Z
dc.date.available 2018-05-28T10:45:22Z
dc.date.issued 2018 es
dc.identifier.citation Bezerra, Natanael-Victor-Furtunato ; Leite, Karla-Lorene-de França ; de Medeiros, Mariana-Marinho-Davino ; Martins, Mariana-Leonel ; Cardoso, Andrea-Medeiros-Rodrigues ; Alves, Pollianna-Muniz ; Padilha, Wilton-Wilney-Nascimento ; Cavalcanti, Yuri-Wanderley. Impact of the anatomical location, alcoholism and smoking on the prevalence of advanced oral cancer in Brazil. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 23 3 2018: 7- es
dc.identifier.uri http://hdl.handle.net/10550/66435
dc.description.abstract To evaluate the prevalence of oral cancer in Brazil according to the clinical stage, anatomical location, alcoholism and smoking. Data referring to 31,217 cases of oral cancer, from 2000 to 2010, were obtained from the Integrator Module of the Hospital Registry of Cancer. Inconsistent data (?non-classified? cases) was eliminated and 21,160 cases were analyzed. The frequency distribution according to clinical stage, anatomical location, alcoholism and smoking was analyzed descriptively and through a binary logistic regression model (?<0.05). The clinical stage (dependent variable) was dichotomized in early stage (I and II) or advanced stage (III and IV). The year of diagnosis, anatomical location and deleterious habits (alcoholism and smoking) were considered independent variables. The most frequent characteristics were: oropharynx location (n=3856, 18.41%), clinical stage IV (n=11924, 56.09%) and combined use of alcohol and tobacco (n=19226; 61.59%). The year 2009 (p<0.01, PR = 1.162, CI-95%=1.053-1.283) and location at the base of tongue (p<0.01, PR = 2.485, CI-95% = 2.182-2.807) presented a higher prevalence ratio for advanced stage oral cancer. The combined use of alcohol and tobacco showed a higher prevalence rate for the advanced clinical stage of cancer (p<0.01, PR =1.449, CI-95%=1.382-1.520) if compared to individuals without habits, or just alcoholics. Higher prevalence of advanced stage of oral cancer is related to the localization at the base of the tongue and to the concomitant use of alcohol and tobacco. Therefore, it can be suggested that all these characteristics lead to a worse prognosis of oral cancer. es
dc.title Impact of the anatomical location, alcoholism and smoking on the prevalence of advanced oral cancer in Brazil es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.22318 es
dc.type.hasVersion VoR es_ES

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