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In vitro assessment of the antifungal effects of neem powder added to polymethyl methacrylate denture base material

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In vitro assessment of the antifungal effects of neem powder added to polymethyl methacrylate denture base material

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dc.contributor.author Hamid, Shorouq-Khalid es
dc.contributor.author Al-Dubayan, AlAnoud-Hamad es
dc.contributor.author Al-Awami, Heba es
dc.contributor.author Khan, Soban-Qadir es
dc.contributor.author Gad, Mohammed-Moustafa es
dc.date.accessioned 2019-04-01T12:02:11Z
dc.date.available 2019-04-01T12:02:11Z
dc.date.issued 2019 es
dc.identifier.citation Hamid, Shorouq-Khalid ; Al-Dubayan, AlAnoud-Hamad ; Al-Awami, Heba ; Khan, Soban-Qadir ; Gad, Mohammed-Moustafa. In vitro assessment of the antifungal effects of neem powder added to polymethyl methacrylate denture base material. En: Journal of Clinical and Experimental Dentistry, 11 2 2019: 170-178 es
dc.identifier.uri http://hdl.handle.net/10550/69679
dc.description.abstract Denture with antimicrobial activities is desirable to prevent Candida albican adhesion subsequently decreasing the susceptibility of denture stomatitis incidence. Azadirachta Indica, commonly known as Neem powder has antimicrobial effect but the effect of its addition to acrylic denture base on C. albicans adhesion has not been investigated. The aim of this study was determine whether adding neem powder to acrylic denture base materials could reduce Candida albicansadhesion. One hundred and twenty acrylic resin denture specimens were fabricated and divided into heat-polymerized (n=60) and auto-polymerized (n=60) groups. Each group was further divided into 6 groups (n=10) based on the neem concentration: 0, 0.5, 1, 1.5, 2 and 2.5 wt% of the polymer. After polymerization, the specimens were polished, stored in distilled water, sonicated, sterilized, submerged in artificial saliva containing C. albicans, and finally, placed in an incubator at 37°C. Slide counting and direct culture methods were used to assess the antifungal effects of the neem addition. An analysis of variance and post hoc Tukey?s test were performed for the data analysis (p?0.05 was statistically significant). Based on the results, the neem addition significantly decreased the C. albicans count when compared to the control group (p?0.05). Moreover, the count decreased as the neem concentration increased (lowest count with 2.5 wt%). The results suggest that adding neem powder to acrylic resin denture base materials reduces the adhesion of C. albicans; therefore, the incorporation of neem could be a possible denture stomatitis prevention method. es
dc.title In vitro assessment of the antifungal effects of neem powder added to polymethyl methacrylate denture base material es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.55458 es
dc.type.hasVersion VoR es_ES

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