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Frequency, intensity and localization of pain as risk factors for frailty in older adults

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Frequency, intensity and localization of pain as risk factors for frailty in older adults

dc.contributor.author	Rodríguez Sánchez, Isabel
dc.contributor.author	García Esquinas, Esther
dc.contributor.author	Mesas, Arthur E.
dc.contributor.author	Martín Moreno, José María
dc.contributor.author	Rodríguez-Mañas, Leocadio
dc.contributor.author	Rodríguez Artalejo, Fernando
dc.date.accessioned	2019-05-20T07:52:15Z
dc.date.available	2019-05-20T07:52:15Z
dc.date.issued	2018
dc.identifier.citation	Rodríguez Sánchez, Isabel García Esquinas, Esther Mesas, Arthur E. Martín Moreno, Jose María Rodríguez-Mañas, Leocadio Rodríguez Artalejo, Fernando 2018 Frequency, intensity and localization of pain as risk factors for frailty in older adults Age and Ageing 48 1 74 80
dc.identifier.uri	http://hdl.handle.net/10550/70233
dc.description.abstract	Background: the association between pain characteristics and frailty risk is uncertain. Objective: to investigate the separate impact of the frequency, intensity and location of pain on frailty risk and its possible mechanisms. Methods: prospective cohort of 1505 individuals ≥63 years followed between 2012 and 2015 in Spain. In 2012, pain was classified into: lowest pain (Score 0), middle pain (Score 1-4) and highest pain (Score 5-6). Incident frailty was assessed in 2015 as having ≥3 Fried criteria or a Frailty Index (FI) ≥0.30. Results: in multivariate analyses, the risk of frailty (measured with the Fried criteria or the FI) increased progressively with the frequency of pain, its intensity and the number of pain locations. Compared with those having the lowest pain score, the odds ratio (95% confidence interval) of Fried-based frailty was 1.24 (0.56-2.75) in the middle score and 2.39 (1.34-4.27; P-trend <0.01) in the highest score. Corresponding values for frailty as FI ≥0.30 were 1.39 (0.80-2.42) and 2.77 (1.81-4.24; P-trend <0.01). Odds ratios did not change after adjustment for alcohol intake, Mediterranean diet adherence or sedentary time, but were reduced with adjustment for pain-associated chronic diseases (cardiovascular disease, diabetes, chronic lung disease, osteomuscular disease and depression). A higher pain score was linked to higher risk of exhaustion and low physical activity (two out of five Fried criteria) and to a worse score in all FI domains. Conclusion: frequency, intensity and location of pain were associated with higher risk of frailty. Study associations were partly explained by pain-associated morbidity.
dc.relation.ispartof	Age and Ageing, 2018, vol. 48, num. 1, p. 74-80
dc.subject	Gerontologia
dc.title	Frequency, intensity and localization of pain as risk factors for frailty in older adults
dc.type	journal article	es_ES
dc.date.updated	2019-05-20T07:52:15Z
dc.identifier.doi	10.1093/ageing/afy163
dc.identifier.idgrec	133047
dc.rights.accessRights	open access	es_ES