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Dentin-pulp complex reactions in conventional and radiation-related caries : a comparative study

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Dentin-pulp complex reactions in conventional and radiation-related caries : a comparative study

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dc.contributor.author Fonsêca, Jéssica-Montenegro es
dc.contributor.author Palmier, Natalia es
dc.contributor.author Silva, Wagner-Gomes es
dc.contributor.author Morais-Faria, Karina es
dc.contributor.author Vargas, Pablo Agustín es
dc.contributor.author Lopes, Márcio Ajudarte es
dc.contributor.author Salvajoli, João-Victor es
dc.contributor.author Brandao, Thais-Bianca es
dc.contributor.author Ribeiro, Ana-Carolina-Prado es
dc.contributor.author Almeida, José Flávio Affonso de es
dc.contributor.author Goes, Mario Fernando es
dc.contributor.author Santos Silva, Alan Roger es
dc.date.accessioned 2019-07-02T09:21:06Z
dc.date.available 2019-07-02T09:21:06Z
dc.date.issued 2019 es
dc.identifier.citation Fonsêca, Jéssica-Montenegro ; Palmier, Natalia ; Silva, Wagner-Gomes ; Morais-Faria, Karina ; Vargas, Pablo Agustín ; Lopes, Márcio Ajudarte ; Salvajoli, João-Victor ; Brandao, Thais-Bianca ; Ribeiro, Ana-Carolina-Prado ; Almeida, José Flávio Affonso de ; Goes, Mario Fernando ; Santos Silva, Alan Roger. Dentin-pulp complex reactions in conventional and radiation-related caries : a comparative study. En: Journal of Clinical and Experimental Dentistry, 11 3 2019: 236-243 es
dc.identifier.uri https://hdl.handle.net/10550/70627
dc.description.abstract Radiation-related caries (RRC) is one of the most significant oral toxicities of head and neck radiotherapy (HNRT); however, the potential of radiation to directly cause harmful dentin and pulpal effects and impair response to caries progression is controversial. Therefore, the aim of this study was to characterize the reactions of the dentin-pulp complex in teeth affected by RRC. Patients and methods: Twenty-two carious teeth extracted from 22 head and neck cancer (HNC) patients were divided into control (conventional caries; n=11) and irradiated (RRC; n=11) groups and paired matched by dental homology, clinical patterns of caries progression following the Post-Radiation Dental Index (PRDI) and microscopic depth of carious invasion. Histopathological characteristics based on morphological hierarchy, cell populations of dental pulp, blood vessels, neural elements, extracellular matrix components, inflammation, patterns of carious invasion and reactionary dentin presence were evaluated by optical light microscopy and histomorphometry. Mean PRDI scores were 3.2 for the control group and 3.8 for the irradiated group. Dentin demineralization patterns were also similar between the groups and the mean depths of demineralization were 1,158.58µm and 1,056.89µm for the control and irradiated groups, respectively. Pulp histopathological changes and dentin reaction patterns were similar between groups and varied according to the PRDI scores and carious lesions depth. Dentin and pulp reactions are highly preserved in RRC teeth. es
dc.title Dentin-pulp complex reactions in conventional and radiation-related caries : a comparative study es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.55370 es
dc.type.hasVersion VoR es_ES

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